- SOX12 Promotes Thyroid Cancer Cell Proliferation and Invasion by Regulating the Expression of POU2F1 and POU3F1
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Su Z, Bao W, Yang G, Liu J, Zhao B
- KMID: 2530381
- Yonsei Med J.
- 2022 Jun;63(6):591-600.
- doi: 10.3349/ymj.2022.63.6.591
Purpose: SOX12 is overexpressed in many cancers, and we aimed to explore the biological function and mechanism of SOX12 in thyroid cancer. Materials and Methods: We first analyzed the expression of... -
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- MiR-103a-3p Contributes to the Progression of Colorectal Cancer by Regulating GREM2 Expression
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Zhang Z, Zhu X
- KMID: 2530372
- Yonsei Med J.
- 2022 Jun;63(6):520-529.
- doi: 10.3349/ymj.2022.63.6.520
Purpose: Our research aimed to investigate the influence of miR-103a-3p on the growth and apoptosis of colorectal cancer (CRC) cells. Materials and Methods: Bioinformatics was employed to analyze differentially expressed microRNAs... -
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- Gymnemic Acid Ameliorates Pancreatic β-Cell Dysfunction by Modulating Pdx1 Expression: A Possible Strategy for β-Cell Regeneration
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Kannan P, Raghunathan M, Mohan T, Palanivelu S, Periandavan K
- KMID: 2530151
- Tissue Eng Regen Med.
- 2022 Jun;19(3):603-616.
- doi: 10.1007/s13770-022-00435-7
BACKGROUND: Endogenous pancreatic β-cell regeneration is a promising therapeutic approach for enhancing β-cell function and neogenesis in diabetes. Various findings have reported that regeneration might occur via stimulating β-cell proliferation,... -
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- Insulin enhances neurite extension and myelination of diabetic neuropathy neurons
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Pham VM, Thakor N
- KMID: 2527767
- Korean J Pain.
- 2022 Apr;35(2):160-172.
- doi: 10.3344/kjp.2022.35.2.160
Background: The authors established an In Vitro model of diabetic neuropathy based on the culture system of primary neurons and Schwann cells (SCs) to mimic similar symptoms observed in in... -
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- AC092127.1-miR-451a-AE binding protein 2 Signaling Facilitates Malignant Properties of Breast Cancer
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Zhang X, Cong L, Xu D, Leng Q, Shi M, Zhou Y
- KMID: 2519862
- J Breast Cancer.
- 2021 Aug;24(4):389-401.
- doi: 10.4048/jbc.2021.24.e37
Purpose: The purpose of the current study was to explore the functions and potential mechanism of miR-451a in breast cancer (BC). Methods: Quantitative reverse transcription real-time polymerase chain reaction was used... -
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- Sepsis induces variation of intestinal barrier function in different phase through nuclear factor kappa B signaling
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Cao YY, Wang ZH, Xu QC, Chen Q, Wang Z, Lu WH
- KMID: 2516876
- Korean J Physiol Pharmacol.
- 2021 Jul;25(4):375-383.
- doi: 10.4196/kjpp.2021.25.4.375
The intestinal barrier function disrupted in sepsis, while little is known about the variation in different phases of sepsis. In this study, mouse models of sepsis were established by caecal... -
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- Long Non-Coding RNA NORAD Inhibits Breast Cancer Cell Proliferation and Metastasis by Regulating miR-155-5p/ SOCS1 Axis
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Liu W, Zhou X, Li Y, Jiang H, Chen A
- KMID: 2517346
- J Breast Cancer.
- 2021 Jun;24(3):330-343.
- doi: 10.4048/jbc.2021.24.e32
Purpose: Non-coding RNA activated by DNA damage (NORAD) has been reported to be a cancer-related long non-coding RNA (lncRNA) implicated in the progression of several cancers; however, its role in... -
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- Signaling Role of Adipocyte Leptin in Prostate Cell Proliferation Induced by Trichomonas vaginalis
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Kim JH, Han IH, Shin SJ, Park SY, Chung HY, Ryu JS
- KMID: 2517054
- Korean J Parasitol.
- 2021 Jun;59(3):235-249.
- doi: 10.3347/kjp.2021.59.3.235
Leptin is a type of adipokine mainly produced by adipocytes and reported to be overproduced in prostate cancer. However, it is not known whether it stimulates the proliferation of prostate... -
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- Anti-proliferative and apoptotic effects of hull-less pumpkin extract on human papillary thyroid carcinoma cell line
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Bahadori MH, Azari Z, Zaminy A, Dabirian S, Mehrdad SM, Kondori BJ
- KMID: 2514590
- Anat Cell Biol.
- 2021 Mar;54(1):104-111.
- doi: 10.5115/acb.20.228
Papillary thyroid carcinoma (PTC) is one of the most common cancers of the endocrine system. Previous studies have shown that the extract of hull-less pumpkin seed (HLPS) has a significant... -
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- Dysregulated Dermal Mesenchymal Stem Cell Proliferation and Differentiation Interfered by Glucose Metabolism in Psoriasis
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Zhao X, Xing J, Li J, Hou R, Niu X, Liu R, Jiao J, Yang X, Li J, Liang J, Zhou L, Wang Q, Chang W, Yin G, Li X, Zhang K
- KMID: 2513085
- Int J Stem Cells.
- 2021 Feb;14(1):85-93.
- doi: 10.15283/ijsc20073
Background and Objectives: Psoriasis is a chronic inflammatory skin disease, which the mechanisms behind its initiation and development are related to many factors. DMSCs (dermal mesenchymal stem cells) represent an... -
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- Modulation of Vascular Smooth Muscle Cell Phenotype by High Mobility Group AT-Hook 1
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Jung Y, Lee HS, Ha JM, Jin SY, Kum HJ, Vafaeinik F, Ha HK, Song SH, Kim CD, Bae SS
- KMID: 2512932
- J Lipid Atheroscler.
- 2021 Jan;10(1):99-110.
- doi: 10.12997/jla.2021.10.1.99
Objective: The purpose of this study is to examine the effect of high mobility group AT-hook 1 (HMGA1) on the phenotyptic change of vascular smooth muscle cells (VSMCs). Methods: Gene silencing... -
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- The proper concentrations of dextrose and lidocaine in regenerative injection therapy: in vitro study
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Woo MS, Park J, Ok SH, Park M, Sohn JT, Cho MS, Shin IW, Kim YA
- KMID: 2510308
- Korean J Pain.
- 2021 Jan;34(1):19-26.
- doi: 10.3344/kjp.2021.34.1.19
Background: Prolotherapy is a proliferation therapy as an alternative medicine. A combination of dextrose solution and lidocaine is usually used in prolotherapy. The concentrations of dextrose and lidocaine used in... -
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- Two intertwined compartments coexisting in sporadic conventional colon adenomas
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Rubio CA
- KMID: 2512097
- Intest Res.
- 2021 Jan;19(1):12-20.
- doi: 10.5217/ir.2019.00133
Sporadic conventional colon adenomas are microscopically built of 2 intertwined compartments: one on top, harboring the dysplastic tissue that defines their histo-biomolecular attributes, and the other below, composed of non-dysplastic... -
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- Coordination of Multiple Cellular Processes by NR5A1/Nr5a1
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Morohashi Ki, Inoue M, Baba T
- KMID: 2511002
- Endocrinol Metab.
- 2020 Dec;35(4):756-764.
- doi: 10.3803/EnM.2020.402
The agenesis of the gonads and adrenal gland in revealed by knockout mouse studies strongly suggested a crucial role for Nr5a1 (SF-1 or Ad4BP) in organ development. In relation to... -
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- High mobility group box 3 promotes cervical cancer proliferation by regulating Wnt/β-catenin pathway
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Zhuang S, Yu X, Lu M, Li Y, Ding N, Ding Y
- KMID: 2512056
- J Gynecol Oncol.
- 2020 Nov;31(6):e91.
- doi: 10.3802/jgo.2020.31.e91
Objective: High mobility group box 3 (HMGB3) plays an important role in the development of various cancer. This study aims to explore whether HMGB3 regulates cervical cancer (CC) progression and... -
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- Deletion Timing of Cic Alleles during Hematopoiesis Determines the Degree of Peripheral CD4+ T Cell Activation and Proliferation
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Park GY, Lee GW, Kim S, Hong H, Park JS, Cho JH, Lee Y
- KMID: 2511870
- Immune Netw.
- 2020 Oct;20(5):e43.
- doi: 10.4110/in.2020.20.e43
Capicua (CIC) is a transcriptional repressor that regulates several developmental processes. CIC deficiency results in lymphoproliferative autoimmunity accompanied by expansion of CD44hiCD62Llo effector/memory and follicular Th cell populations. Deletion of... -
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- LncRNA DLG1-AS1 Promotes Cancer Cell Proliferation in Triple Negative Breast Cancer by Downregulating miR-203
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Li S
- KMID: 2511795
- J Breast Cancer.
- 2020 Aug;23(4):343-354.
- doi: Triple negative breast neoplasms
Purpose: The oncogenic role of long non-coding RNA (lncRNA) DLG1-AS1 has been studied in cervical cancer, but its involvement in triple negative breast cancer (TNBC) is unknown. Here, we aimed... -
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- G Protein–Coupled Receptor 30 Mediates the Anticancer Effects Induced by Eicosapentaenoic Acid in Ovarian Cancer Cells
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Zhao Y, Zhao MF, Yang ML, Wu TY, Xu CJ, Wang JM, Li CJ, Li X
- KMID: 2504462
- Cancer Res Treat.
- 2020 Jul;52(3):815-829.
- doi: 10.4143/crt.2019.380
Purpose While numerous epidemiological studies have indicated that omega-3 polyunsaturated fatty acids have anticancer properties in various cancers, the effects and mechanisms of eicosapentaenoic acid (EPA) in ovarian cancer cell growth... -
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- Cellular Response of Ventricular-Subventricular Neural Progenitor/Stem Cells to Neonatal Hypoxic-Ischemic Brain Injury and Their Enhanced Neurogenesis
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Shin JE, Lee H, Jung K, Kim M, Hwang K, Han J, Lim J, Kim IS, Lim KI, Park KI
- KMID: 2502230
- Yonsei Med J.
- 2020 Jun;61(6):492-505.
- doi: 10.3349/ymj.2020.61.6.492
Purpose: To elucidate the brain’s intrinsic response to injury, we tracked the response of neural stem/progenitor cells (NSPCs) located in ventricular-subventricular zone (V-SVZ) to hypoxic-ischemic brain injury (HI). We also... -
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- Function of hepatocyte growth factor in gastric cancer proliferation and invasion
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Koh SA, Lee KH
- KMID: 2501412
- Yeungnam Univ J Med.
- 2020 Apr;37(2):73-78.
- doi: 10.12701/yujm.2019.00437
Cancer incidence has been increasing steadily and is the leading cause of mortality worldwide. Gastric cancer is still most common malignancy in Korea. Cancer initiation and progression are multistep processes... -
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