- Hypoxia Pretreatment Promotes Chondrocyte Differentiation of Human Adipose-Derived Stem Cells via Vascular Endothelial Growth Factor
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Hwang OK, Noh YW, Hong JT, Lee JW
- KMID: 2502558
- Tissue Eng Regen Med.
- 2020 Jun;17(3):335-350.
- doi: 10.1007/s13770-020-00265-5
BACKGROUND: Human adipose tissue-derived stem cells (ADSCs) are attractive multipotent stem cell sources with therapeutic potential in various fields requiring repair and regeneration, such as acute and chronically damaged tissues.... -
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- Evaluation of Collagen Gel-Associated Human Nasal Septum- Derived Chondrocytes As a Clinically Applicable Injectable Therapeutic Agent for Cartilage Repair
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Lim MH, Jeun JH, Kim DH, Park SH, Kim SJ, Lee WS, Hwang SH, Lim JY, Kim SW
- KMID: 2502562
- Tissue Eng Regen Med.
- 2020 Jun;17(3):387-399.
- doi: 10.1007/s13770-020-00261-9
BACKGROUND: Articular cartilage injury has a poor repair ability and limited regeneration capacity with therapy based on articular chondrocytes (ACs) implantation. Here, we validated the hypothesis that human nasal septum-derived... -
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- Current Update of Cartilage Regeneration Using Stem Cells in Osteoarthritis
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Seon JK, Choi IS, Ko JW
- KMID: 2469879
- J Korean Orthop Assoc.
- 2019 Dec;54(6):478-489.
- doi: 10.4055/jkoa.2019.54.6.478
Osteoarthritis is a disease characterized by the progression of articular cartilage erosion, that increases pain during joint motion and reduces the ability to withstand mechanical stress, which in turn limits... -
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- Perspective on Intra-articular Injection Cell Therapy for Osteoarthritis Treatment
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Im GI
- KMID: 2455045
- Tissue Eng Regen Med.
- 2019 Aug;16(4):357-363.
- doi: 10.1007/s13770-018-00176-6
BACKGROUND: Osteoarthritis (OA), the most common arthritis, is one of the most frequently encountered orthopaedic conditions. As a small number of large joints such as knee and hip are affected... -
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- Mechanically Reinforced Extracellular Matrix Scaffold for Application of Cartilage Tissue Engineering
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Oh HJ, Kim SH, Cho JH, Park SH, Min BH
- KMID: 2411877
- Tissue Eng Regen Med.
- 2018 Jun;15(3):287-299.
- doi: 10.1007/s13770-018-0114-1
Scaffolds with cartilage-like environment and suitable physical properties are critical for tissue-engineered cartilage repair. In this study, decellularized porcine cartilage-derived extracellular matrix (ECM) was utilized to fabricate ECM scaffolds. Mechanically... -
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- Non-contact Coculture Reveals a Comprehensive Response of Chondrocytes Induced by Mesenchymal Stem Cells Through Trophic Secretion
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Xu L, Wu Y, Liu Y, Zhou Y, Ye Z, Tan WS
- KMID: 2405966
- Tissue Eng Regen Med.
- 2018 Feb;15(1):37-48.
- doi: 10.1007/s13770-017-0084-8
Coculture between mesenchymal stem cells (MSCs) and chondrocytes has significant implications in cartilage regeneration. However, a conclusive understanding remains elusive. Previously, we reported that rabbit bone marrow-derived MSCs (rbBMSCs) could... -
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- Magnetic Resonance Imaging (MRI) of a Hypertrophy of Cartilage and Simultaneous Regeneration of a Damaged Meniscus after Autologous Bone Marrow Aspirates Concentrate (BMAC) Transplantation: a Case Report and Literature Review
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Bae SH, Kim HJ, Oh E, Hwang J, Hong SS, Hwang JH
- KMID: 2392691
- Investig Magn Reson Imaging.
- 2017 Sep;21(3):187-191.
- doi: 10.13104/imri.2017.21.3.187
Bone marrow aspirates concentrate (BMAC) transplantation is a well-known technique for cartilage regeneration with good clinical outcomes for symptoms in patients with osteoarthritis (OA). Magnetic resonance imaging (MRI) has an... -
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- Alginate-Hyaluronic Acid-Collagen Composite Hydrogel Favorable for the Culture of Chondrocytes and Their Phenotype Maintenance
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Mahapatra , Jin GZ, Kim HW
- KMID: 2360802
- Tissue Eng Regen Med.
- 2016 Oct;13(5):538-546.
- doi: 10.1007/s13770-016-0059-1
Articular cartilage has limited regeneration capacity, thus significant challenge has been made to restore the functions. The development of hydrogels that can encapsulate and multiply cells, and then effectively maintain... -
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- Chondrogenic Effect of Transplanted Type I Collagen Scaffold within Subperichondrial Cartilage Defect
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Lee HG, Son DG, Han KH, Kim JH, Lee SY
- KMID: 2203416
- J Korean Soc Plast Reconstr Surg.
- 2005 Jul;32(4):521-528.
The purpose of this research is to find out the degree of cartilage regeneration by inserting the atelo- collagen scaffold obtained from dermis of a calf on cartilage defect site.... -
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- Optical Coherence Tomography Analysis of the Rabbit Articular Cartilage after Chondrocyte Transplantation
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Han CW, Kim JY, Choi WS, Kim CK, Lee JH, Pan Y
- KMID: 2104896
- J Korean Orthop Res Soc.
- 2002 Oct;5(2):93-99.
PURPOSE: To evaluate the ability of optical coherence tomography (OCT) to provide real-time, high-resolution structural analysis of the full thickness rabbit articular repair tissue following chondrocyte transplantation. MATERIALS AND METHODS: Full... -
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- The Effect of an Artificial Dermis on Chondrogenesis from Perichondrium
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Kim DG, Shin DP, Park JW, Cho BC, Baik BS, Yoon KT
- KMID: 2119713
- J Korean Soc Plast Reconstr Surg.
- 2001 Jan;28(1):37-43.
The purpose of this study is to investigate the effect of artificial dermis(Terudermis(R)) on cartilage induction from perichondrium. A total of 24 rabbits were used and divided into control(n =... -
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