- Parathyroid Hormone-Related Protein Promotes the Proliferation of Patient-Derived Glioblastoma Stem Cells via Activating cAMP/PKA Signaling Pathway
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Guo Z, Huang T, Liu Y, Liu C
- KMID: 2545231
- Int J Stem Cells.
- 2023 Aug;16(3):315-325.
- doi: 10.15283/ijsc22097
Background and Objectives: Glioblastoma (GBM) is an aggressive primary brain tumor characterized by its hetero-geneity and high recurrence and lethality rates. Glioblastoma stem cells (GSCs) play a crucial role in... -
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- Perampanel ameliorates nitroglycerin-induced migraine through inhibition of the cAMP/ PKA/CREB signaling pathway in the trigeminal ganglion in rats
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Zhai Q, Wang K, Zhang D, Chen J, Dong X, Pan Y
- KMID: 2544245
- Korean J Pain.
- 2023 Jul;36(3):335-346.
- doi: 10.3344/kjp.23039
Background: Perampanel, a highly selective glutamate AMPA receptor antagonist, is widely used to treat epilepsy. Since the existence of common pathophysiological features between epilepsy and migraine, the aim of this... -
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- Effects of School Bullying Prevention Camp on the Adolescent Perpetrators of School Violence
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Lee JJ, Kim JH, Kim BN
- KMID: 2514805
- J Korean Acad Child Adolesc Psychiatry.
- 2021 Apr;32(2):43-50.
- doi: 10.5765/jkacap.200043
Objectives: The purpose of this study was to evaluate the effects of a school bullying prevention camp for adolescent perpetrators of school violence. Methods: A total of 95 adolescents (boys=73, girls=22)... -
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- Cell-type-specific Modulation of Nonhomologous End Joining of Gamma Ray-induced DNA Double-strand Breaks by cAMP Signaling in Human Cancer Cells
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Noh SE, Juhnn YS
- KMID: 2509524
- J Korean Med Sci.
- 2020 Dec;35(48):e371.
- doi: 10.3346/jkms.2020.35.e371
Background: Cyclic AMP (cAMP) signaling is activated by various hormones and neurotransmitters and regulates numerous physiological phenomena, including energy metabolism, gene expression, and proliferation. cAMP signaling plays a role in... -
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- Estrogen Promotes cAMP Production in Mesenchymal Stem Cells by Regulating ADCY2
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Zhao G, Li X, Miao H, Chen S, Hou Y
- KMID: 2500566
- Int J Stem Cells.
- 2020 Mar;13(1):55-64.
- doi: 10.15283/ijsc19139
Background and Objectives: The maternal-fetal interface is an important source of mesenchymal stem cells (MSCs), and it is influenced by high levels of estradiol (E2) during pregnancy. It is highly... -
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- Heat shock protein 70 increases cell proliferation, neuroblast differentiation, and the phosphorylation of CREB in the hippocampus
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Kwon HJ, Kim W, Jung HY, Kang MS, Kim JW, Hahn KR, Yoo DY, Yoon YS, Hwang IK, Kim DW
- KMID: 2470012
- Lab Anim Res.
- 2019 Dec;35(4):154-164.
- doi: 10.1186/s42826-019-0020-2
In the present study, we investigated the effects of heat shock protein 70 (HSP70) on novel object recognition, cell proliferation, and neuroblast differentiation in the hippocampus. To facilitate penetration into... -
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- The Effects of the 2030 Diabetes Camp Program on Depression, Anxiety, and Stress in Diabetic Patients
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Jung JH, Lee JH, Camp Committee
- KMID: 2458970
- J Korean Diabetes.
- 2019 Sep;20(3):194-204.
- doi: 10.4093/jkd.2019.20.3.194
BACKGROUND: The purpose of this study was to evaluate the effects of the 2030 Diabetes Camp program on depression, anxiety, and stress among diabetic patients. METHODS: This study enrolled diabetic patients... -
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- The Role and Significance of Medical Social Worker Intervention in Camps for Diabetic Patients
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Kim TH
- KMID: 2442364
- J Korean Diabetes.
- 2018 Dec;19(4):246-254.
- doi: 10.4093/jkd.2018.19.4.246
In diabetes camps, medical social workers interact with individuals and groups of participants to help them learn to adapt psychologically and emotionally to the stress from diabetes and to improve... -
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- Fatty Acid Increases cAMP-dependent Lactate and MAO-B-dependent GABA Production in Mouse Astrocytes by Activating a G(αs) Protein-coupled Receptor
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Lee N, Sa M, Hong YR, Lee CJ, Koo J
- KMID: 2424731
- Exp Neurobiol.
- 2018 Oct;27(5):365-376.
- doi: 10.5607/en.2018.27.5.365
Medium-chain fatty acids (MCFAs) are mostly generated from dietary triglycerides and can penetrate the blood-brain barrier. Astrocytes in the brain use MCFAs as an alternative energy source. In addition, MCFAs... -
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- Anti-inflammatory and utero-relaxant effect of α-bisabolol on the pregnant human uterus
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Muñoz-Pérez VM, Ortiz MI, Ponce-Monter HA, Monter-Pérez V, Barragán-RamÃrez G
- KMID: 2414263
- Korean J Physiol Pharmacol.
- 2018 Jul;22(4):391-398.
- doi: 10.4196/kjpp.2018.22.4.391
The aim of this study was to evaluate the in vitro anti-inflammatory and utero-relaxant effect of α-bisabolol on the pregnant human myometrium. Samples from the pregnant human myometrium were used... -
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- The Memory-Enhancing Effects of Liquiritigenin by Activation of NMDA Receptors and the CREB Signaling Pathway in Mice
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Ko YH, Kwon SH, Hwang JY, Kim KI, Seo JY, Nguyen TL, Lee SY, Kim HC, Jang CG
- KMID: 2429049
- Biomol Ther.
- 2018 Mar;26(2):109-114.
- doi: 10.4062/biomolther.2016.284
Liquiritigenin (LQ) is a flavonoid that can be isolated from Glycyrrhiza radix. It is frequently used as a tranditional oriental medicine herbal treatment for swelling and injury and for detoxification.... -
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- Cilostazol attenuates kainic acid-induced hippocampal cell death
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Park YS, Jin Z, Jeong EA, Yi CO, Lee JY, Park IS, Roh GS
- KMID: 2398556
- Korean J Physiol Pharmacol.
- 2018 Jan;22(1):63-70.
- doi: 10.4196/kjpp.2018.22.1.63
Cilostazol is a selective inhibitor of type 3 phosphodiesterase (PDE3) and has been widely used as an antiplatelet agent. Cilostazol mediates this activity through effects on the cyclic adenosine monophosphate... -
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- Lipolytic effect of novel extracts from mulberry (Morus alba) leaves fermented with Cordyceps militaris in the primary adipocytes derived from SD rats
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Lee MR, Kim JE, Yun WB, Choi JY, Park JJ, Kim HR, Song BR, Choi YW, Kim KM, Hwang DY
- KMID: 2391102
- Lab Anim Res.
- 2017 Sep;33(3):270-279.
- doi: 10.5625/lar.2017.33.3.270
Mulberry (Morus alba) leaves are known to have therapeutic effects on lipid metabolism including lipogenesis, lipolysis and hyperlipidemia. However, novel compounds with strong lipolytic ability among 27 extracts of the... -
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- The Study on the Lives and Health Conditions of Internees in Santo Thomas Camp of Philippines: Based on McAnlis's The War in Manila (1941–1945)
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LEE J, CHO Y
- KMID: 2391245
- Korean J Med Hist.
- 2017 Aug;26(2):265-314.
- doi: 10.13081/kjmh.2017.26.265
When Japan invaded the Philippines, two missionary dentists (Dr. McAnlis and Dr. Boots) who were forced to leave Korea were captured and interned in the Santo Thomas camp in Manila.... -
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- Relaxant and anti-inflammatory effect of two thalidomide analogs as PDE-4 inhibitors in pregnant rat uterus
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Muñoz-Pérez VM, Fernández-MartÃnez E, Ponce-Monter H, Ortiz MI
- KMID: 2384457
- Korean J Physiol Pharmacol.
- 2017 Jul;21(4):429-437.
- doi: 10.4196/kjpp.2017.21.4.429
The aim of this study was to evaluate the relaxant and anti-inflammatory effects of two thalidomide analogs as phosphodiesterase-4 (PDE-4) inhibitors in pregnant rat uterus. Uteri from Wistar female rats... -
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- Diabetes Camp as Continuing Education for Diabetes Self-Management in Middle-Aged and Elderly People with Type 2 Diabetes Mellitus
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Park SY, Kim SY, Lee HM, Hur KY, Kim JH, Lee MK, Sim KH, Jin SM
- KMID: 2376772
- Diabetes Metab J.
- 2017 Apr;41(2):99-112.
- doi: 10.4093/dmj.2017.41.2.99
BACKGROUND: Despite the established benefits of diabetes camps for the continuing education of children with type 1 diabetes mellitus, little is known about the long-term metabolic benefits of diabetes camps... -
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- Wogonin Attenuates Hippocampal Neuronal Loss and Cognitive Dysfunction in Trimethyltin-Intoxicated Rats
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Lee B, Sur B, Cho SG, Yeom M, Shim I, Lee H, Hahm DH
- KMID: 2164226
- Biomol Ther.
- 2016 May;24(3):328-337.
- doi: 10.4062/biomolther.2015.152
We examined whether wogonin (WO) improved hippocampal neuronal activity, behavioral alterations and cognitive impairment, in rats induced by administration of trimethyltin (TMT), an organotin compound that is neurotoxic to these... -
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- Shoulder and Elbow Injury Rates and Patterns in Korean Rookie Professional Baseball Pitchers
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Park JY, Lee SJ, Kim YI, Heo GY
- KMID: 2162171
- Clin Should Elbow.
- 2016 Mar;19(1):15-19.
- doi: 10.5397/cise.2016.19.1.15
BACKGROUND: To investigate how many rookie pitchers suffered from injuries while playing in the amateur league without guidelines for prevention of excessive pitching, we analyzed their amateur pitching patterns based... -
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- cAMP induction by ouabain promotes endothelin-1 secretion via MAPK/ERK signaling in beating rabbit atria
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Peng LQ, Li P, Zhang QL, Hong L, Liu LP, Cui X, Cui BR
- KMID: 2150468
- Korean J Physiol Pharmacol.
- 2016 Jan;20(1):9-14.
- doi: 10.4196/kjpp.2016.20.1.9
Adenosine 3',5'-cyclic monophosphate (cAMP) participates in the regulation of numerous cellular functions, including the Na(+)-K(+)-ATPase (sodium pump). Ouabain, used in the treatment of several heart diseases, is known to increase... -
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- Comparative Analysis of Dibutyric cAMP and Butyric Acid on the Differentiation of Human Eosinophilic Leukemia EoL-1 Cells
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Jung Y
- KMID: 2132705
- Immune Netw.
- 2015 Dec;15(6):313-318.
- doi: 10.4110/in.2015.15.6.313
Purification of enough numbers of circulating eosinophils is difficult because eosinophils account for less than 5% peripheral blood leukocytes. Human eosinophilic leukemia EoL-1 cells have been considered an in vitro... -
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