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Cardiovascular Safety Pharmacology of Sibutramine

Yun J, Chung E, Choi KH, Cho DH, Song YJ, Han KM, Cha HJ, Shin JS, Seong WK, Kim YH, Kim HS

Sibutramine is an anorectic that has been banned since 2010 due to cardiovascular safety issues. However, counterfeit drugs or slimming products that include sibutramine are still available in the market....
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Comparison of arylalkylamine N-acetyltransferase and melatonin receptor type 1B immunoreactivity between young adult and aged canine spinal cord

Ahn JH, Park JH, Kim IH, Lee JC, Yan BC, Yong MS, Lee CH, Choi JH, Yoo KY, Hwang IK, Moon SM, Shin HC, Won MH

Melatonin affects diverse physiological functions through its receptor and plays an important role in the central nervous system. In the present study, we compared immunoreactivity patterns of arylalkylamine N-acetyltransferase (AANAT),...
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Electroretinography recordings using a light emitting diode active corneal electrode in healthy beagle dogs

Itoh Y, Maehara S, Itoh N, Yamashita , Izumisawa

Electroretinography (ERG) is a well-established diagnostic procedure for objectively evaluating retinal function. In this study, ERG in beagle dogs, which are a popular experimental animal, was performed to determine the...
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Basic data on the hematology, serum biochemistry, urology, and organ weights of beagle dogs

Choi SY, Hwang JS, Kim IH, Hwang DY, Kang HG

This study was conducted to provide basic data on physiological and hematological characteristics, and organ weights of beagle dogs. A total of 237 beagle dogs were used to determine differences...
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Effects of Ficus carica paste on constipation induced by a high-protein feed and movement restriction in beagles

Oh HG, Lee HY, Seo MY, Kang YR, Kim JH, Park JW, Kim OJ, Back HI, Kim SY, Oh MR, Park SH, Kim MG, Jeon JY, Hwang MH, Shin SJ, Chae SW

Constipation is one of the most common functional digestive complaints worldwide. We investigated the laxative effects of figs (Ficus carica L) in a beagle model of constipation induced by high...
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A Tumoral Calcinosis Case in a Beagle Dog

Shin SK, Kim G, Chang D, Na KJ, Ahn B

  • KMID: 2312068
  • Lab Anim Res.
  • 2010 Jun;26(2):215-218.
We describe a case of tumoral calcinosis in a 13-month-old female Beagle dog presenting for surgical removal of a 4x3x3 cm mass in the soft tissues of the medial right...
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Pulp response of beagle dog to direct pulp capping materials: Histological study

Bae JH, Kim YG, Yoon PY, Cho BH, Choi YH

The purpose of this study was to evaluate the pulp tissue reaction to direct pulp capping of mechanically exposed beagle dogs'pulp with several capping materials. A total of 36 teeth...
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Histological evaluation of direct pulp capping with DSP-derived synthetic peptide in beagle dog

Kim JH, Hong JB, Lim BS, Cho BH

The purpose of this study was to investigate the pulpal response to direct pulp capping with dentin sialoprotein (DSP)-derived synthetic peptide in teeth of dogs, and to compare its efficacy...
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Study on osseointegration of a Korean Transitional implant system in beagle dog

Lee WJ, Jung JW, Kim YS, Pi SH, You HK, Shin HS

  • KMID: 2462865
  • J Korean Acad Periodontol.
  • 2006 Mar;36(1):253-263.
PURPOSE: Recently, dental implant systems have been widely used for the treatment of the extraction site, but we have been confronted with many limitations in esthetics, phonetics and function. Transitional...
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Effects of Tetracycline-loaded Poly(L-lactide) Barrier Membranes on Guided Bone Regeneration in Beagle Dog

Choi KS, Kim T, Yang DS, Kim EC, You HK, Shin HS

Application of membranes for guided tissue regeneration(GTR) have been confined to the subgingival barrier functions; however, many studies have provided evidence that some drugs, including tetracycline, initially can promote the...
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A Short-Term Study of the Effects of UDCA on Gingival Inflammation in the Beagle Dog

Park SH, Han SM, Choi SM, Ku Y, Rhyu IC, Han SB, Lee HM, Kim MM, Kim SN, Chung CP

  • KMID: 2421321
  • J Korean Acad Periodontol.
  • 1999 Mar;29(1):1-14.
Ursodeoxycholic acid(UDCA) is a hydrophilic gall bladder acid and has been used as a effective drug for liver disease related to immunity. This drug inhibits secretions of IL-2, IL-4, and...
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