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Development of a UPLC-MS/MS method for the therapeutic monitoring of L-asparaginase

Jeong HC, Kim T, Yang DH, Shin KH

This study aimed to develop a UPLC-MS/MS method for determining plasma levels of L-aspartic acid and L-asparagine and the activity of L-asparaginase. L-aspartic acid, L-asparagine, and L-aspartic acid-2,3,3-d3 were extracted...
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Partial Purification of the L-Asparaginase from Escherichia Coli and a Study on its Enzymatic Properties

Pak RJ

  • KMID: 1677536
  • Korean J Urol.
  • 1973 Sep;14(3):155-163.
1. Based on the differences in solubility in ammonium sulfate and activity as a function of pH, two L-asparaginases, EC-1 and 2, were partially purified from Escherichia coli 0112. 2....
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Studies of Enzymes in Hyman Skin Tissue

Kim YP, Kahng JB

  • KMID: 1920678
  • Korean J Dermatol.
  • 1976 Jun;14(2):115-121.
Gamma-glutamyl transpeptidase (GGTP) activity was measured in the homogenate of penile foreskin, using y-glutamyl-p-nitroanilide, as a substrate, and it was found that (GGTP) activity was present in the epidermis and...
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Correlation Between Gastric Emptying and Gastric Adaptive Relaxation Influenced by Amino Acids

Uchida M, Kobayashi , Saito C

  • KMID: 2387831
  • J Neurogastroenterol Motil.
  • 2017 Jul;23(3):400-408.
  • doi: 10.5056/jnm16153
BACKGROUND/AIMS: Amino acids have many physiological activities. We report the correlation between gastric emptying and gastric adaptive relaxation using tryptophan and amino acids with a straight alkyl chain, hydroxylated chain,...
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Response of Achlya racemosa, A. proliferoides and Saprolegnia furcata to Sub-lethal Treatments of Amino Acids

Ali EH

  • KMID: 2312405
  • Mycobiology.
  • 2003 Jun;31(2):86-94.
The effect of four sub-lethal concentrations (400, 800, 1,200 and 1,600 microg/ml) of three amino acids such as isoluecine, aspartic acid and phenylalanine on vegetative growth and sexual and asexual...
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Effects of RGD Protein on the Bone Resorptive Activity of Osteoclast

Chang JS, Kim KY, Kim YT, Lee CS, Han BH, Hong SW

  • KMID: 2190008
  • J Korean Orthop Assoc.
  • 1997 Apr;32(2):457-463.
Osteoclasts resorb bone by the hydrogen ions and proteolytic enzymes in the localize environment under the ruffled border. Before releasing hydrogen ion and enzymes, osteoclast should attach to bone surface...
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Alterations of Amino Acid Level in Depressed Rat Brain

Yang P, Li X, Ni J, Tian J, Jing F, Qu C, Lin L, Zhang H

Amino-acid neurotransmitter system dysfunction plays a major role in the pathophysiology of depression. Several studies have demonstrated the potential of amino acids as a source of neuro-specific biomarkers could be...
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Nutritional and Physicochemical Characteristics of the Antidementia Acetylcholinesterase-Inhibiting Methanol Extracts from Umbilicaria esculenta

Lee JS, Min GH, Lee JS

To develop new antidementia nutraceuticals, a potent acetylcholinesterase (AChE)-inhibiting extract was screened from various extracts of nutritional mushrooms and lichens nutritional and its physicochemical properties were investigated. Among the several...
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Leaf Exudates of Vicia faba and their Effects on Botrytis fabae and Some Associated Fungi

Migahed FF, Nofel AM

  • KMID: 2052967
  • Mycobiology.
  • 2001 Dec;29(4):198-204.
Analysis of leaf exudates of Vicia faba using paper chromatography to identify individual amino acids and sugars qualitatively was investigated. The results revealed that the number of identified amino acids...
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Effects of High and Low Sodium Diet on Plasma Amino Acid Levels in Korean Adult Women

Hong WJ, Sung CJ, Kim MH

  • KMID: 2269730
  • Korean J Nutr.
  • 2004 Mar;37(2):108-114.
This study was performed to determine the effect of dietary Na levels on plasma amino acid levels. Plasma amino acid levels were compared in 20 adult healthy women subjects who...
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Nanoliposomes of L-lysine-conjugated poly(aspartic acid) Increase the Generation and Function of Bone Marrow-derived Dendritic Cells

Im SA, Kim KH, Ji HG, Yu HG, Park SK, Lee CK

BACKGROUND: Biodegradable polymers have increasingly been recognized for various biological applications in recent years. Here we examined the immunostimulatory activities of the novel poly(aspartic acid) conjugated with L-lysine (PLA). METHODS: PLA...
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Antitumor and Antioxidant Activities of the Extracts from Fruiting Body of Phellinus linteus

Lee JW, Baek SJ, Bae WC, Park JM, Kim YS

  • KMID: 2312501
  • Mycobiology.
  • 2006 Dec;34(4):230-235.
Fruiting bodies of Phellinus linteus were extracted by hot water and alkali methods. Sugar contents of PL-H (hot water extract) and PL-A (alkali water extract) were 81.1%, 37.4% and protein...
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Effects of Some Amino Acids on Ammonia Secretion and Extracellular Protease Activity by Three Oomycetes in Synthetic Medium with or without Glucose

Ali EH

The effects of different concentrations of three amino acids as carbon and or nitrogen sources on mycelial dry weights, changes in pH values of synthetic medium, ammonia secretion and extracellular...
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Bioavailability of Aspartic Acid Chelated Calcium in Calcium Deficient Rats

Park MG, Ha TY, Shin KS

Calcium (Ca) is an essential element to maintain body homeostasis. However, many factors disturb calcium absorption. Aspartic acid chelated calcium (AAC) was synthesized by new methods using calcium carbonate and...
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The Amino Acid Compositions of Formula for Children with Inherited Metabolic Disorder

Ryu KH, Kim JS, Lee EH, Kwon IS, Hahn SH

  • KMID: 2335559
  • J Korean Pediatr Soc.
  • 2002 Jan;45(1):37-43.
PURPOSE: This study aimed to determine the amino acids composition, safety and efficacy of formulas recently developed by Korean dairy companies for children with inherited metabolic disorder. METHODS: The determination of...
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Cortical Laminar Necrosis associated with Osmotic Demyelination Syndrome

Cho AH, Choi CG, Lee SA

Cortical laminar necrosis has been rarely observed in osmotic demyelination syndrome. We report a 32-year-old female patient who became comatose after the rapid correction of hyponatremia. There were high signal...
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Influence of Physiological and Environmental Factors on Growth and Sporulation of an Antagonistic Strain of Trichoderma viride RSR 7

Jayaswal R, Singh R, Lee YS

Influence of physiological and environmental factors on an antagonistic strain of Trichoderma viride RSR7 were studied optimize its biocontrol potential. The growth and sporulation of T. viride was greatly influenced...
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Recipe Standardization and Nutrient Analysis of Local Foods of Cheollabuk-do Province(The Second Report)

Choo JJ, Shin MK, Kwon KS, Yoon GS

  • KMID: 2367916
  • Korean J Community Nutr.
  • 2001 May;6(2):250-258.
Five representative local foods of Cheollabuk-do Province such as chuotang, ochuk, baekhapchuk, dasulgitang and minmulgokimaeuntang were subjected to recipe standardization and nutrient analysis. To derive a standard recipe, first a...
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ras Gene Mutations in Malignant Fibrous Histiocytoma

Yoo J, Lee AW, Kang SJ, Kim BK

  • KMID: 2275609
  • Korean J Pathol.
  • 2001 Jun;35(3):232-237.
BACKGROUND: ras gene mutations have been described in various human malignancies, suggesting that their activation may play a role in oncogenesis. However, there are few reports concerning ras gene alterations...
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Paper chromatographic study on the amino acids of some parasitic helminths

Seo BS, Yoon JS, Lee SH

Unidimensional and two dimensional paper choromatogram were prepared of 10 kinds of parastic helminths. Fourteen amino acids were identified from the acid hydrolysed tissue proteins of A. lumbricoides(cuticle and musculature),...
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