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Effect of Diet and Water Intake on Aquaporin 2 Function

Kim JM, Kim TH, Wang T

Appropriate control of diet and water intake is important for maintaining normal blood pressure, fluid and electrolyte homeostasis in the body. It is relatively understood that the amount of sodium...
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Membrane Trafficking of Collecting Duct Water Channel Protein AQP2 Regulated by Akt/AS160

Jung HJ, Kwon TH

  • KMID: 2406195
  • Electrolyte Blood Press.
  • 2010 Dec;8(2):59-65.
Akt (protein kinase B (PKB)) is a serine/threonine kinase that acts in the phosphatidylinositol 3-kinase (PI3K)/Akt signaling pathway. The PI3K/Akt signaling pathway, triggered by growth factors and hormones including vasopressin,...
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Expression of Aquaporin-2 in the Inner Ear of Water-Deprived Guinea Pigs

Lee SS, Kim K, Kim JH, Cho HH, Jang CH, Cho YB

BACKGROUND AND OBJECTIVES: Although the role of aquaporin-2 (AQP2) in the kidney has been well defined, its role in the inner ear remains to be determined. The present study was...
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Ubiquitination of Aquaporin: in the kidney

Lee YJ, Kwon TH

Ubiquitination is known to be important for endocytosis and lysosomal degradation of aquaporin-2 (AQP2). Ubiquitin (Ub) is covalently attached to the lysine residue of the substrate proteins and activation and...
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Vasopressin and Vasopressin Receptor Antagonists

Oh YK

Vasopressin, a neurohypophyseal peptide hormone, is the endogenous agonist at V1a, V1b, and V2 receptors. The most important physiological function of vasopressin is the maintenance of water homeostasis through interaction...
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Regulation of AQP2 in Collecting Duct: An emphasis on the Effects of Angiotensin II or Aldosterone

Lee BH, Kwon TH

Vasopressin, angiotensin II (AngII), and aldosterone are essential hormones in the regulation of body fluid homeostatsis. We examined the effects of AngII or aldosterone on the regulation of body water...
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Two Novel Mutations in the Aquaporin 2 Gene in a Girl with Congenital Nephrogenic Diabetes Insipidus

Cheong HI, Cho SJ, Zheng SH, Cho HY, Ha IS, Choi Y

Congenital nephrogenic diabetes insipidus (CNDI) is a rare inherited disorder characterized by insensitivity of the kidney to the antidiuretic effect of vasopressin. There are three inheritance patterns of CNDI: the...
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