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Differentiation and Transdifferentiation of Lens Epithelial Cells in Capsular Bag Model Culture

Yoon JH, Lee MI, Park SM, Kim YK, Oh JH

  • KMID: 2125786
  • J Korean Ophthalmol Soc.
  • 2004 Dec;45(12):2105-2118.
PURPOSE: To investigate the differentiation of lens epithelial cells (LECs) to lens fiber, and the transdifferentiation of LECs to fibroblast in capsular bag culture. METHODS: After observing the changes of...
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Accumulation and Aberrant Modifications of alpha-Crystallins in Anterior Polar Cataracts

Hwang KH, Lee EH, Jho EH, Kim JH, Lee DH, Chung SK, Kim EK, Joo CK

Crystallins are the major proteins found in the lens, and the localization of specific crystallins is well known. Overexpression and accumulation of alphaB-crystallin has been observed in response to stress...
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Transdifferentiation of Cultured Bovine Lens Epithelial Cells into Myofibroblast-like Cells by Serum Modulation

Kim JT, Lee EH, Chung KH, Kang IC, Lee DH, Joo CK

An after-cataract is caused by the proliferation of residual cells over the equator of the lens. These cells subsequently migrate to the posterior lens capsule, where they undergo aberrant differentiation...
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