- Outcomes and Factors Associated with Completion of Radium‑223 Therapy
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Liu R, Juwara L, Ferrario C, Probst S
- KMID: 2534410
- Nucl Med Mol Imaging.
- 2022 Oct;56(5):228-235.
- doi: 10.1007/s13139-022-00760-8
Purpose Radium-223 has been demonstrated in clinical trials to improve survival in castration-resistant prostate cancer (CRPC) patients with bone metastases. However, its performance in routine use remains to be fully... -
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- Chronic obstructive pulmonary disease severity in middle-aged and older men with steoporosis associates with decreased bone formation
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Tsukamoto M, Mori T, Nakamura E, Okada Y, Fukuda H, Yamanaka Y, Sabanai K, Wang KY, Hanagiri T, Kuboi S, Yatera K, Sakai A
- KMID: 2509973
- Osteoporos Sarcopenia.
- 2020 Dec;6(4):179-187.
- doi: 10.1016/j.afos.2020.11.003
Objectives Chronic obstructive pulmonary disease (COPD) is a risk factor for osteoporosis. Nevertheless, much remains unclear regarding the bone metabolism dynamics associated with COPD. The present study focuses on the associations... -
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- A Correlation between Serum Level of Alkaline Phosphatase and Acne Severity in Children and Adolescents: A Retrospective Cross-Sectional Study
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Jue MS, Park E, Kang HS, Kim JS
- KMID: 2500757
- Ann Dermatol.
- 2020 Jun;32(3):206-212.
- doi: 10.5021/ad.2020.32.3.206
Background: Acne is a chronic inflammatory disease of the pilosebaceous unit and usually affects adolescents when the peak concentrations of growth hormone, insulin-like growth factor 1, and androgen are demonstrated.... -
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- Case Report of Lethal Perinatal Hypophosphatasia with Seizure and Respiratory Failure Diagnosed by ALPL Gene Mutation
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Lee SJ, Lee DW, Kim WD
- KMID: 2502090
- Neonatal Med.
- 2020 Feb;27(1):26-30.
- doi: 10.5385/nm.2020.27.1.26
Hypophosphatasia is a rare disease characterized by defective bone mineralization due to deficiency of tissue-nonspecific alkaline phosphatase. The patient was an 8-day-old male infant who presented with seizure since that... -
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- Nationwide Cross-sectional Study of Association between Pterygium and Alkaline Phosphatase in a Population from Korea
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Kim HJ, Rah SH, Kim SW, Kim SH
- KMID: 2468471
- J Korean Ophthalmol Soc.
- 2020 Jan;61(1):9-16.
- doi: 10.3341/jkos.2020.61.1.9
PURPOSE: We determined whether elevated serum alkaline phosphatase (ALP) was related to prevalence, location, type, length, and recurrence of pterygium in a population from the Republic of Korea. METHODS: A nationwide... -
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- The Prognostic Value of Albumin-to-Alkaline Phosphatase Ratio before Radical Radiotherapy in Patients with Non-metastatic Nasopharyngeal Carcinoma: A Propensity Score Matching Analysis
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Kim JS, Keam B, Heo DS, Han DH, Rhee CS, Kim JH, Jung KC, Wu HG
- KMID: 2460581
- Cancer Res Treat.
- 2019 Oct;51(4):1313-1323.
- doi: 10.4143/crt.2018.503
PURPOSE: We first analyzed the prognostic power of albumin-to-alkaline phosphatase ratio (AAPR) before radical radiotherapy (RT) in non-metastatic nasopharyngeal carcinoma (NPC) patients. MATERIALS AND METHODS: The records of 170 patients with... -
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- Evaluation of Challenges in Diagnosis of Spontaneous Subacute Pyogenic Spondylodiscitis in Immunocompetent Patients: Experiences from a Tertiary Care Center
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Pandita N, Paul S, Yadav G, Kalia RB, Kandwal P
- KMID: 2455653
- Asian Spine J.
- 2019 Aug;13(4):621-629.
- doi: 10.31616/asj.2018.0220
STUDY DESIGN: Prospective clinical study. PURPOSE: We evaluated the challenges faced during diagnosis and management of patients with subacute pyogenic discitis and discussed various clues in clinical history, radiologic and hematologic... -
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- Serum alkaline phosphatase and γ-glutamyl transferase in acute pyelonephritis
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Han C, Lee YK, Park HC, Cho A, Choi SR, Yoon JW, Koo JR, Kim HJ, Noh JW, Park MJ
- KMID: 2451870
- Kidney Res Clin Pract.
- 2019 Jun;38(2):205-211.
- doi: 10.23876/j.krcp.18.0074
BACKGROUND: Elevated serum alkaline phosphatase (AP) and γ-glutamyl transferase (γ-GT) are commonly observed in patients with acute pyelonephritis. The goal of this study was to examine the clinical significance of... -
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- Stabilization of serum alkaline phosphatase in hemodialysis patients by implementation of local chronic kidney disease-mineral bone disorder management strategy: A quality improvement study
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Jin K, Ban TH, Jung JY, Kim AJ, Kim Y, Lee SY, Yang DH, Choi BS, Oh KH, Kim J, Kwon YJ, Choi JW, Kim GH
- KMID: 2416084
- Kidney Res Clin Pract.
- 2018 Jun;37(2):157-166.
- doi: 10.23876/j.krcp.2018.37.2.157
BACKGROUND: The aim of this study is to narrow the gap between global guidelines and local practices, we recently established domestic recommendations by adapting the international guidelines for management of... -
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- Pilot Algorithm Designed to Help Early Detection of HMG-CoA Reductase Inhibitor-Induced Hepatotoxicity
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Hong JY, Kim HS, Choi IY
- KMID: 2403310
- Healthc Inform Res.
- 2017 Jul;23(3):199-207.
- doi: 10.4258/hir.2017.23.3.199
OBJECTIVES: To enable early detection of adverse drug reactions (ADRs) in patients using HMG-CoA reductase inhibitors (statins), we developed an algorithm that automatically detects liver injury caused by statins from... -
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- Melanin extract from Gallus gallus domesticus promotes proliferation and differentiation of osteoblastic MG-63 cells via bone morphogenetic protein-2 signaling
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Yoo HS, Chung KH, Lee KJ, Kim DH, An JH
- KMID: 2407766
- Nutr Res Pract.
- 2017 Jun;11(3):190-197.
- doi: 10.4162/nrp.2017.11.3.190
BACKGROUND/OBJECTIVES: Gallus gallus domesticus (GD) is a natural mutant breed of chicken in Korea with an atypical characterization of melanin in its tissue. This study investigated the effects of melanin... -
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- Bone turnover rate and bone formation/resorption balance during the early stage after switching from a bone resorption inhibitor to denosumab are predictive factors of bone mineral density change
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Nakatoh S
- KMID: 2377002
- Osteoporos Sarcopenia.
- 2017 Mar;3(1):45-52.
- doi: 10.1016/j.afos.2016.12.001
OBJECTIVES: This study aimed to investigate the correlation between bone mineral density (BMD) and the turnover rate [√(MoMf²+ MoMr²), multiple of median formation (MoMf) was calculated as bone-specific alkaline phosphatase... -
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- Clinical Factors Associated With Trabecular Bone Score in Koreans: A Retrospective Study
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Chung EH, Lee SH, Kim JH, Park HJ, Min HY, Kim SH, Yun JM, Cho BL
- KMID: 2415678
- Ann Geriatr Med Res.
- 2016 Dec;20(4):190-194.
- doi: 10.4235/agmr.2016.20.4.190
BACKGROUND: The objective of our study was to examine the clinical factors associated with bone microarchitecture in Koreans. To the best of our knowledge, only a few studies have investigated... -
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- Assessment of the Role of Noni (Morinda citrifolia) Juice for Inducing Osteoblast Differentiation in Isolated Rat Bone Marrow Derived Mesenchymal Stem Cells
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Hussain S, Tamizhselvi R, George L, Manickam V
- KMID: 2362516
- Int J Stem Cells.
- 2016 Nov;9(2):221-229.
- doi: 10.15283/ijsc16024
BACKGROUND AND OBJECTIVES: Morinda citrifolia (Noni), an important traditional medicinal plant still used in patients with bone fractures or dislocation to promote connective tissue repair and to reduce inflammation. However,... -
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- Differentiation of Rat Dermal Mesenchymal Cells and Calcification in Three-Dimensional Cultures
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Suyama T, Hatta M, Hata S, Ishikawa H, Yamazaki J
- KMID: 2360801
- Tissue Eng Regen Med.
- 2016 Oct;13(5):527-537.
- doi: 10.1007/s13770-016-9124-z
Three-dimensional (3D) cultures are known to promote cell differentiation. Previously, we investigated the differentiation of rat dermal fibroblasts to α-smooth muscle actin (α-SMA)-positive myofibroblasts through transforming growth factor (TGF)-β production... -
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- Effects of Scytosiphon lomentaria on osteoblastic proliferation and differentiation of MC3T3-E1 cells
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Park MH, Kim S, Cheon J, Lee J, Kim BK, Lee SH, Kong C, Kim YY, Kim M
- KMID: 2313911
- Nutr Res Pract.
- 2016 Apr;10(2):148-153.
- doi: 10.4162/nrp.2016.10.2.148
BACKGROUND/OBJECTIVES: Bone formation and bone resorption continuously occur in bone tissue to prevent the accumulation of old bone, this being called bone remodeling. Osteoblasts especially play a crucial role in... -
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- Bone Marrow Mesenchymal Stem Cell Transplantation in a Rabbit Corneal Alkali Burn Model (A Histological and Immune Histo-chemical Study)
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Ahmed SK, Soliman AA, Omar SM, Mohammed W
- KMID: 2380800
- Int J Stem Cells.
- 2015 May;8(1):69-78.
- doi: 10.15283/ijsc.2015.8.1.69
BACKGROUND: Alkali-burned corneas can seldom heal properly to restore corneal transparency. Treatment of this severe disorder of the ocular surface remains a challenge. AIM OF THE WORK: was to investigate whether... -
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- Growth Properties and Pluripotency Marker Expression of Spontaneously Formed Three-dimensional Aggregates of Human Adipose-derived Stem Cells
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Bogdanova-Jatniece A, Berzins U, Kozlovska
- KMID: 1974602
- Int J Stem Cells.
- 2014 Nov;7(2):143-152.
- doi: 10.15283/ijsc.2014.7.2.143
BACKGROUND AND OBJECTIVES: Recent findings suggest that therapeutic potential of mesenchymal stem cells (MSCs) could be increased through aggregation into three-dimensional (3D) bodies, and different culture methods have been employed... -
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- Clinical Characteristics of Primary Epstein Barr Virus Hepatitis with Elevation of Alkaline Phosphatase and gamma-Glutamyltransferase in Children
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Yang SI, Geong JH, Kim JY
- KMID: 1779893
- Yonsei Med J.
- 2014 Jan;55(1):107-112.
- doi: 10.3349/ymj.2014.55.1.107
PURPOSE: The aim of the present study was to evaluate the clinical characteristics of the primary Epstein-Barr virus (EBV) hepatitis with elevation of both serum alkaline phosphatase (ALP) and gamma-glutamyltransferase... -
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- The difference in serum alkaline phosphatase levels between girls with precocious puberty and those with normal puberty
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Jwa HJ, Yang SI, Lim HH
- KMID: 2266354
- Ann Pediatr Endocrinol Metab.
- 2013 Dec;18(4):191-195.
- doi: 10.6065/apem.2013.18.4.191
PURPOSE: Serum alkaline phosphatase (ALP) level is the most valid marker of bone formation. Precocious puberty (PP) in girls is characterized by early growth acceleration. The aim of this study... -
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