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Current knowledge about biomarkers of acute kidney injury in liver cirrhosis

Lee HA, Seo YS

Acute kidney injury (AKI) is common in advanced cirrhosis. Prerenal azotemia, hepatorenal syndrome, and acute tubular necrosis are the main causes of AKI in patients with cirrhosis. Evaluation of renal...
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Poor Prognosis of Contrast-Induced Nephropathy during Long Term Follow Up

Liu T, Lee SR

Contrast-induced nephropathy (CIN) is known to associate with poor prognosis. However, there have been few studies for long-term follow up. The purpose of this study was to know the prognosis of...
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Is acute kidney injury after laparoscopic adrenalectomy related to the progression of chronic kidney disease in patients with primary aldosteronism?

Yoon JH, Chung HS, Hong AR, Kim HK, Kang HC, Kim MS, Hwang EC, Jung SI, Park K, Kwon D

Purpose: This study was conducted to investigate the predictors of kidney outcome after laparoscopic adrenalectomy in patients with primary aldosteronism (PA). Materials and Methods: We retrospectively reviewed the medical records of...
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Nephrotoxicity of cancer therapeutic drugs: Focusing on novel agents

Hong MH

Kidney injury caused by anticancer agents is a common problem that can interfere with and affect the dose intensity of anticancer therapy, thus restricting patient survival. Recent advances in targeted...
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Mortality predictors in critically ill patients with acute kidney injury requiring continuous renal replacement therapy

Medina-Liabres KRP, Jeong JC, Oh HJ, An JN, Lee JP, Kim DK, Ryu DR, Kim S

Background: Because of high cost of continuous renal replacement therapy (CRRT) and the high mortality rate among severe acute kidney injury patients, careful identification of patients who will benefit from...
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Intestinal microbiota and kidney diseases

Kim MG, Yang J, Jo SK

Large microbial communities reside in the gut as an endogenous organ and interact with the host physiology through symbiotic relationships, affecting health. Recent advances in high-throughput sequencing techniques have made...
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Renal Safety of Repeated Intravascular Administrations of Iodinated or Gadolinium-Based Contrast Media within a Short Interval

Kwon C, Kang KM, Choi YH, Yoo RE, Sohn CH, Han SS, Yoon SH

Objective: We aimed to investigate whether repeated intravascular administration of iodinated contrast media (ICM) or gadolinium-based contrast agents (GBCAs) within a short interval was associated with an increased risk of...
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Perfusion parameters during cardiopulmonary bypass as a predictor of acute kidney injury after aortic valve replacement

Lee Y, Kim SH, Hwang HY, Sohn SH, Choi JW, Kim KH

Background: Acute kidney injury (AKI) is a major complication after cardiac surgery and significantly affects postoperative mortality and morbidity. This study was conducted to evaluate the association between target pump...
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Predictive Value of Plasma NGAL:Hepcidin-25 for Major Adverse Kidney Events After Cardiac Surgery with Cardiopulmonary Bypass: A Pilot Study

Albert C, Haase M, Albert A, Ernst M, Kropf S, Bellomo R, Westphal S, Braun-Dullaeus RC, Haase-Fielitz A, Elitok S

Background: Neutrophil gelatinase-associated lipocalin (NGAL) and hepcidin-25 are involved in catalytic iron-related kidney injury after cardiac surgery with cardiopulmonary bypass. We explored the predictive value of plasma NGAL, plasma hepcidin-25,...
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Hepcidin-25 as a Novel Kidney Biomarker for Cardiac Surgery-Associated Acute Kidney Injury

Cho SY, Hur M

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Factors Contributing to an Efficacious Endovascular Treatment for Acute Ischemic Stroke in Asian Population

Lee JS, Hwang YH, Sohn SI

Although randomized control trials about endovascular treatment (EVT) of emergent large vessel occlusion (LVO) have demonstrated the success of mechanical thrombectomy as the choice of treatment, a wide range of...
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Role of Akt1 in renal fibrosis and tubular dedifferentiation during the progression of acute kidney injury to chronic kidney disease

Kim IY, Park YK, Song SH, Seong EY, Lee DW, Bae SS, Lee SB

Background/Aims: Acute kidney injury (AKI) is an underestimated yet important risk factor for the development of chronic kidney disease (CKD), characterized by tubulointerstitial fibrosis and tubular dedifferentiation. Tubular dedifferentiation, which...
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Association between measurement time of fractional excretion rate of sodium and mid-long term clinical prognosis in acute kidney injury patients

Kim TH, Choi HS, Park SS, Lee JG, Ryu HS, Min DK

  • KMID: 2517704
  • J Korean Soc Emerg Med.
  • 2021 Jun;32(3):242-248.
Objective: Rapid identification of the cause for acute kidney injury (AKI) is very crucial. Among the diagnostic indicators of AKI, the fractional excretion rate of sodium (FENa) is clinically considered...
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Risk factors to predict post-contrast acute kidney injury after contrast-enhanced computed tomography in the emergency department

Choi SY, Yu G, Kong T, Choa M, Chung HS, Chung SP

  • KMID: 2517703
  • J Korean Soc Emerg Med.
  • 2021 Jun;32(3):231-241.
Objective: This study aimed to investigate the risk factors of post-contrast acute kidney injury (PAKI) and the usefulness of the Mehran score for predicting PAKI in patients who underwent contrast-enhanced...
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Uric acid albumin ratio as a predictive marker of short-term mortality in patients with acute kidney injury

Özgür Y, Akın S, Yılmaz NG, Gücün M, Keskin

Objective We aimed to investigate uric acid and albumin ratio (UA/A) as a marker of short-term mortality in acute kidney injury (AKI). Both uric acid and albumin are strongly correlated...
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Acute kidney injury and mortality in coronavirus disease 2019: results from a cohort study of 1,280 patients

Chebotareva N, Berns S, Berns A, Androsova T, Lebedeva M, Moiseev S

Background: The development of acute kidney injury (AKI) in patients with coronavirus disease 2019 (COVID-19) is associated with a high risk of death. Published data demonstrate the possibility of severe...
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Twenty-four-hour serum creatinine variation is associated with poor outcome in the novel coronavirus disease 2019 (COVID-19) patients

Alfano G, Ferrari A, Fontana F, Mori G, Ligabue G, Giovanella S, Magistroni R, Meschiari M, Franceschini E, Menozzi M, Cuomo G, Orlando G, Santoro A, Di Gaetano M, Puzzolante C, Carli F, Bedini A, Milic J, Mussini C, Cappelli G, Guaraldi G, for the Modena Covid-19 Working Group (MoCo19)

Background: The development of acute kidney injury (AKI) in patients with coronavirus disease 2019 (COVID-19) is associated with a high risk of death. Published data demonstrate the possibility of severe...
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Quantitative Analysis of Microperfusion in ContrastInduced Nephropathy Using Contrast-Enhanced Ultrasound: An Animal Study

Seo N, Oh H, Oh HJ, Chung YE

Objective: To investigate imaging biomarkers of microperfusion in contrast-induced nephropathy (CIN) using contrastenhanced ultrasound (CEUS). Materials and Methods: The CIN model was fabricated by administering indomethacin (10 mg/kg), L-NAME (15 mg/kg),...
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Analysis of the risk factors of acute kidney injury after total hip or knee replacement surgery

Lee YJ, Park BS, Park S, Park JH, Kim IH, Ko J, Kim YW

Background: Postoperative acute kidney injury (AKI), which increases the risk of postoperative morbidity and mortality, poses a major concern to surgeons. We conducted this study to analyze the risk factors...
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T helper 17 cells in the pathophysiology of acute and chronic kidney disease

Basile DP, Ullah MM, Collet JA, Mehrotra P

Both acute and chronic kidney disease have a strong underlying inflammatory component. This review focuses primarily on T helper 17 (Th17) cells as mediators of inflammation and their potential to...
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