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Differential modulation of zinc-stimulated p21(Cip/WAF1) and cyclin D1 induction by inhibition of PI3 kinase in HT-29 colorectal cancer cells

Oh SY, Park KS, Kim AJ, Choi KY

  • KMID: 1093594
  • Exp Mol Med.
  • 2002 Mar;34(1):27-31.
Activation of the extra cellular signal regulated kinase (ERK) pathway is involved in both proliferation and growth arrest of cells depending on intensity and duration of stimuli. In this study,...
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Effect of metal ions on the stability of metallothionein in the degradation by cellular fractions in vitro

Hahn SH, Yoo OJ, Gahl WA

  • KMID: 755115
  • Exp Mol Med.
  • 2001 Mar;33(1):32-36.
Metallothioneins (MT), small molecular weight metal binding proteins are known to play an important protective role against heavy metal toxicity, either as antioxidants or pre-oxidants. However, the mode of metabolic...
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