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Selective Expansion of Natural Killer Cells from Peripheral Blood Mononuclear Cells by K562 Cell Line and IL-2

Cho D, Shin SW, Park JS, Kang HK, Kim SK, Pham TN, Zhu XW, Shin MG, Suh SP, Ryang DW, Nam JH, Kim YJ, Lee JJ

BACKGROUND: Several attempts have been made to expand human NK cells from peripheral blood mononuclear cells (PBMCs). This study examined the selective expansion of NK cells using interleukin 2 (IL-2)...
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Induction of Myeloma Cell Line-specific Cytotoxic T Lymphocytes using Monocyte-derived Dendritic Cells Pulsed with Myeloma Cell Line Lysates

Park MS, Park JS, Kang HK, Kim SK, Won JH, Choi BH, Shin SW, Zhu XW, Jin CJ, Pham TN, Cho D, Nam JH, Kim YJ, Kim YK, Yang DH, Chung IJ, Kim HJ, Lee JJ

BACKGROUND: In multiple myeloma (MM), the idiotype (ID) determinant of the paraprotein has been used for immunotherapy using dendritic cells (DCs). However, ID-specific immune responses showed limited clinical responses after...
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