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Intracellular trafficking of TREM2 is regulated by presenilin 1

Zhao Y, Li X, Huang T, Jiang LL, Tan Z, Zhang M, Cheng IH, Wang X, Bu G, Zhang YW, Wang Q, Xu H

Genetic mutations in triggering receptor expressed on myeloid cells 2 (TREM2) have been linked to a variety of neurodegenerative diseases including Alzheimer’s disease, amyotrophic lateral sclerosis, frontotemporal dementia and Parkinson’s...
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Effect of Genetic Polymorphisms of CYP2E1 and ALDH2 on the Relationship between the Levels of Urinary 8-Hydroxydeoxyguanosine and t,t-Muconic Acid

Kim YD, Kang JW, Eom SY, Zhang YW, Kim SH, Kim EY, Lee CH, Moon JD, Kim H

  • KMID: 2028376
  • Korean J Occup Environ Med.
  • 2007 Jun;19(2):164-170.
OBJECTIVES: This study was performed to investigate the effect of genetic polymorphisms on the oxidative genetic damage caused by benzene exposure in workers. METHODS: We measured urinary t,t-muconic acid levels as...
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Effects of Oxidative DNA Damage and Genetic Polymorphism of the Glutathion Peroxidase 1 (GPX1) and 8-Oxoguanine Glycosylase 1 (hOGG1) on Lung Cancer

Lee CH, Lee KY, Choe KH, Hong YC, Noh SI, Eom SY, Ko YJ, Zhang YW, Yim DH, Kang JW, Kim H, Kim YD

  • KMID: 792399
  • J Prev Med Public Health.
  • 2006 Mar;39(2):130-134.
OBJECTIVES: Oxidative DNA damage is a known risk factor of lung cancer. The glutathione peroxidase (GPX) antioxidant enzyme that reduces hydrogen peroxide and lipid peroxides plays a significant role...
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