- Emodin ameliorates high-glucose induced mesangial p38 over-activation and hypocontractility via activation of PPARgamma
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Liu Y, Jia L, Liu ZC, Zhang H, Zhang PJ, Wan Q, Wang R
- KMID: 756208
- Exp Mol Med.
- 2009 Sep;41(9):648-655.
- doi: 10.3858/emm.2009.41.9.071
Early stage diabetic nephropathy is characterized by elevated glomerular filtration. Recent studies have identified high-glucose induced p38 MAPK (p38) over-activation in mesangial cells. Mesangial hypocontractility is the major underlying mechanism,... -
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- Machine Learning-Based Prediction of COVID-19 Severity and Progression to Critical Illness Using CT Imaging and Clinical Data
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Purkayastha S, Xiao Y, Jiao Z, Thepumnoeysuk R, Halsey K, Wu J, Tran TML, Hsieh B, Choi JW, Wang D, Vallières M, Wang R, Collins S, Feng X, Feldman M, Zhang PJ, Atalay M, Sebro R, Yang L, Fan Y, Liao Wh, Bai HX
- KMID: 2518657
- Korean J Radiol.
- 2021 Jul;22(7):1213-1224.
- doi: 10.3348/kjr.2020.1104
Objective: To develop a machine learning (ML) pipeline based on radiomics to predict Coronavirus Disease 2019 (COVID-19) severity and the future deterioration to critical illness using CT and clinical variables. Materials... -
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