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Commentary on “Impact of Nonlordotic Sagittal Alignment on Short-term Outcomes of Cervical Disc Replacement”

Zhang K, Liu H, Wu T

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Deep Brain Stimulation of the Subthalamic and Pedunculopontine Nucleus in a Patient with Parkinson's Disease

Liu HG, Zhang K, Yang AC, Zhang JG

Deep brain stimulation (DBS) of the pedunculopontine nucleus (PPN) is a novel therapy developed to treat Parkinson's disease. We report a patient who underwent bilateral DBS of the PPN and...
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Molecular Characteristics and Potent Immunomodulatory Activity of Fasciola hepatica Cystatin

Zhang K, Liu Y, Zhang G, Wang X, Li Z, Shang Y, Ning C, Ji C, Cai X, Xia X, Qiao J, Meng Q

Cystatin, a cysteine protease inhibitor found in many parasites, plays important roles in immune evasion. This study analyzed the molecular characteristics of a cystatin from Fasciola hepatica (FhCystatin) and expressed...
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Prevalence, Risk Factors, and Psychological Effects of Primary Nocturnal Enuresis in Chinese Young Adults

Hu HJ, Zhang ZW, Liang Y, Luo YY, Dou QF, Song CP, Zhang HM, Zhao Y, Tian GR, Zhang K, Mao QF, Song JG, Rittig S, Wen JG

Purpose: This study aimed to investigate the prevalence, risk factors, and effects of primary nocturnal enuresis (PNE) on physical and mental health in young adults in mainland China. Methods: An anonymous...
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Biological Characteristics of Recombinant Arthrobotrys oligospora Chitinase AO-801

Gong S, Meng Q, Qiao J, Huang Y, Zhong W, Zhang G, Zhang K, Li N, Shang Y, Li Z, Cai X

Chitinase AO-801 is a hydrolase secreted by Arthrobotrys oligospora during nematode feeding, while its role remained elusive. This study analyzed the molecular characteristics of recombinant chitinase of Arthrobotrys oligospora (reAO-801)....
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LETM1 Promotes Gastric Cancer Cell Proliferation, Migration, and Invasion via the PI3K/Akt Signaling Pathway

Zhang Y, Chen L, Cao Y, Chen S, Xu C, Xing J, Zhang K

Purpose: Globally, there is a high incidence of gastric cancer (GC). Leucine zipper-EF-hand containing transmembrane protein 1 (LETM1) is reported to play a vital role in several human malignancies. However,...
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Scalded Skin of Rat Treated by Using Fibrin Glue Combined with Allogeneic Bone Marrow Mesenchymal Stem Cells

Yang Y, Zhang W, Li Y, Fang G, Zhang K

  • KMID: 2368147
  • Ann Dermatol.
  • 2014 Jun;26(3):289-295.
BACKGROUND: It is difficult to achieve satisfactory results with the traditional treatment of large-area skin defects and deep burns. OBJECTIVE: To test the treatment effect of an active dressing film made...
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Comparison of Clinical and Radiographic Outcomes Between Transforaminal Endoscopic Lumbar Discectomy and Microdiscectomy: A Follow-up Exceeding 5 Years

Yang X, Zhang S, Su J, Guo S, Ibrahim Y, Zhang K, Tian Y, Wang L, Yuan S, Liu X

Objective: To compare the long-term clinical and radiographic outcomes of transforaminal endoscopic lumbar discectomy (TELD) versus microdiscectomy (MD). Methods: The data of 154 patients with lumbar disc herniation (LDH) who underwent...
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Reference Intervals for Thyroid-Associated Hormones and the Prevalence of Thyroid Diseases in the Chinese Population

Zou Y, Wang D, Cheng X, Ma C, Lin S, Hu Y, Yu S, Xia L, Li H, Yin Y, Liu H, Zhang D, Zhang K, Lian X, Xu T, Qiu L

Background: Thyroid diseases are highly prevalent worldwide, but their diagnosis remains a challenge. We established reference intervals (RIs) for thyroid-associated hormones and evaluated the prevalence of thyroid diseases in China. Methods:...
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Application of HTB-SiHa Cells Transfected with a Recombinant Plasmid for External Quality Assessment of Chlamydia trachomatis PCR

Zhang K, Huo H, Sun Y, Wang L, Zhang R, Lin G, Xie J, Wang Q, Li J

BACKGROUND: The participation of laboratories in external quality assessment (EQA) programs is required for the quality assurance of nucleic acid amplification of Chlamydia trachomatis. This study aimed to construct a...
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Trapping of Methylglyoxal by Sieboldin from Malus baccata L. and Identification of Sieboldin-Methylglyoxal Adducts Forms

Kim JH, Zhang K, Lee J, Gao EM, Lee YJ, Son RH, Syed AS, Kim CY

The methylglyoxal (MGO) trapping constituents from Malus baccata L. were investigated using incubation of MGO and crude extract under physiological conditions followed by HPLC analysis. The peak areas of MGO...
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C-Reactive Protein Gene Variants in Depressive Symptoms & Antidepressants Efficacy

Li X, Sun N, Yang C, Liu Z, Li X, Zhang K

OBJECTIVE: Although the pathogenesis of depression remains unclear, C-reactive protein (CRP) levels are commonly elevated in depressed patients. Thus, CRP single-nucleotide polymorphisms (SNPs) that influence CRP levels may be associated...
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Enhanced recovery after surgery strategy for cirrhosis patients undergoing hepatectomy: experience in a single research center

Zheng Y, Wang L, Wu F, Rong W, Liu Y, Zhang K, Wu J

Purpose: To evaluate the safety and effectiveness of an enhanced recovery after surgery (ERAS) programme after curative liver resection in cirrhotic hepatocellular carcinoma (HCC) patients. Methods: One hundred sixty-two patients were...
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Psoriatic Serum Induce an Abnormal Inflammatory Phenotype and a Decreased Immunosuppressive Function of Mesenchymal Stem Cells

Wang F, Hou R, Li J, Zhao X, Wang Q, Zhang K, Li X

Background and Objectives: Mesenchymal stem cells (MSCs) have immunomodulatory function and participate in the pathogenesis of many immunoregulation-related diseases, including psoriasis. Previously, we found that MSCs from psoriatic lesions overexpress...
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Exploring Contributing Factors to Psychological Traumatic Childbirth from the Perspective of Midwives: A Qualitative Study

Huang D, Dai L, Zeng T, Huang H, Wu M, Yuan M, Zhang K

PURPOSE: As midwives witness and attend the whole process of childbirth, they have a better understanding of which factors may cause traumatic childbirth. However, because most of the studies paid...
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Dysregulated Dermal Mesenchymal Stem Cell Proliferation and Differentiation Interfered by Glucose Metabolism in Psoriasis

Zhao X, Xing J, Li J, Hou R, Niu X, Liu R, Jiao J, Yang X, Li J, Liang J, Zhou L, Wang Q, Chang W, Yin G, Li X, Zhang K

Background and Objectives: Psoriasis is a chronic inflammatory skin disease, which the mechanisms behind its initiation and development are related to many factors. DMSCs (dermal mesenchymal stem cells) represent an...
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The Distinctive Immunologic Pathogenesis Differentiates Atopic Comorbidity Status in Prurigo Nodularis

Chu H, Kim WJ, Kim SM, Kim SH, Kim JH, Zhang K, Kim HL, Kim RW, Lee KH, Park CO

  • KMID: 2538563
  • Korean J Dermatol.
  • 2022 Dec;60(10):666-674.
Background: Prurigo nodularis (PN) is a chronic pruritic skin disorder with a large number of hyperkeratotic nodules. The precise mechanisms of its pathogenesis remain unknown. PN has been linked to...
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Determination of plasma C16-C24 globotriaosylceramide (Gb3) isoforms by tandem mass spectrometry for diagnosis of Fabry disease

Yoon HR, Cho K, Yoo HW, Choi JH, Lee DH, Zhang K, Keutzer J

  • KMID: 1111646
  • J Genet Med.
  • 2007 Jun;4(1):45-52.
PURPOSE: A simple, rapid, and highly sensitive analytical method for Gb3 in plasma was developed without labor-extensive pre-treatment by electrospray ionization MS/MS (ESI-MS/MS). Measurement of globotriaosylceramide (Gb3, ceramide trihexoside) in...
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Extracorporeal photopheresis for refractory rejection in intestinal transplantation

Zhang K, Kumari R, Halma J, Depper J, Bonham CA

Background: Extracorporeal photopheresis (ECP) is an immunomodulatory therapy. Leukopheresed cells are administered 8-methoxypsoralen and exposed to ultraviolet A radiation. ECP has been used in GvHD and treatment of acute and...
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Risk Factors for Duodenal Stump Leakage after Laparoscopic Gastrectomy for Gastric Cancer

Gu L, Zhang K, Shen Z, Wang X, Zhu H, Pan J, Zhong X, Khadaroo P, Chen P

PURPOSE: Duodenal stump leakage (DSL) is a potentially fatal complication that can occur after gastrectomy, but its underlying risk factors are unclear. This study aimed to investigate the risk factors...
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