- 20(S)-Protopanaxadiol enhances angiogenesis via HIF-1α-mediated VEGF secretion by activating p70S6 kinase and benefits wound healing in genetically diabetic mice
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Zhang EY, Gao B, Shi HL, Huang LF, Yang L, Wu XJ, Wang ZT
- KMID: 2395749
- Exp Mol Med.
- 2017 Oct;49(10):e387.
- doi: 10.1038/emm.2017.151
Impaired angiogenesis is one of the crucial factors that impede the wound healing process in diabetic foot ulcers (DFUs). In this study, we found that 20(S)-protopanaxadiol (PPD), an aglycone of... -
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