- Methylation and demethylation of DNA and histones in chromatin: the most complicated epigenetic marker
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Youn HD
- KMID: 2382712
- Exp Mol Med.
- 2017 Apr;49(4):e321.
- doi: 10.1038/emm.2017.38
No abstract available. -
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- A case of leukemia-associated arthritis: identification of leukemic cells in synovial fluid by light microscopy
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Yoon SS, Youn HD, Suh C, Bang YJ, Choi SJ, Kim BK, Kom NK, Kim EC
- KMID: 1421275
- J Korean Med Sci.
- 1987 Dec;2(4):255-258.
- doi: 10.3346/jkms.1987.2.4.255
One case of arthritis complicating leukemia is described in which leukemic cells were identified in synovial fluid by light microscopy. Although arthritis is a well-known manifestation of leukemia with... -
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- The Risk Factors Affecting Ultra-Early Rebleeding In Patients with Spontaneous Subarchnoid Hemorrhage
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Min YI, Heo T, Youn HD
- KMID: 1999063
- J Korean Soc Emerg Med.
- 1997 Sep;8(3):362-367.
Spontaneous subarachnoid hemorrhage(SAH) is a cause of high mortality and morbidity in the emergency department. Rebleeding has been well investigated, and it is now recognized that early operation can prevent... -
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- Down syndrome critical region 1 enhances the proteolytic cleavage of calcineurin
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Lee JE, Jang H, Cho EJ, Youn HD
- KMID: 1058021
- Exp Mol Med.
- 2009 Jul;41(7):471-477.
- doi: 10.3858/emm.2009.41.7.052
Down syndrome critical region 1 (DSCR1), an oxidative stress-response gene, interacts with calcineurin and represses its phosphatase activity. Recently it was shown that hydrogen peroxide inactivates calcineurin by proteolytic cleavage.... -
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- Nur77 upregulates HIF-alpha by inhibiting pVHL-mediated degradation
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Kim BY, Kim H, Cho EJ, Youn HD
- KMID: 1103590
- Exp Mol Med.
- 2008 Feb;40(1):71-83.
- doi: 10.3858/emm.2008.40.1.71
In this study, we investigated the role of Nur77, an orphan nuclear receptor, in HIF-alpha transcriptional activity. We found that Nur77 associates and stabilizes HIF-1alpha via indirect interaction. Nur77 was... -
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- Differential regulation of the histone chaperone HIRA during muscle cell differentiation by a phosphorylation switch
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Yang JH, Song TY, Jo C, Park J, Lee HY, Song I, Hong S, Jung KY, Kim J, Han JW, Youn HD, Cho EJ
- KMID: 2361539
- Exp Mol Med.
- 2016 Aug;48(8):e252.
- doi: 10.1038/emm.2016.68
Replication-independent incorporation of variant histone H3.3 has a profound impact on chromatin function and numerous cellular processes, including the differentiation of muscle cells. The histone chaperone HIRA and H3.3 have... -
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- Antidotes Stocking and Delivery for Acute Poisoning Patients at 20 Emergency Departments in Korea 2015–2017
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Lee S, Youn HD, Chang H, Won S, Kim KH, Oh BJ
- KMID: 2437751
- J Korean Soc Clin Toxicol.
- 2018 Dec;16(2):131-140.
- doi: 10.22537/jksct.2018.16.2.131
PURPOSE: The National Emergency Medical Center has been running a project for the storage and delivery of antidotes for acute poisoning patients of the Department of Health and Welfare, Korea.... -
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- Ctbp2-mediated β-catenin regulation is required for exit from pluripotency
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Kim TW, Kwak S, Shin J, Kang BH, Lee SE, Suh MY, Kim JH, Hwang IY, Lee JH, Choi J, Cho EJ, Youn HD
- KMID: 2395747
- Exp Mol Med.
- 2017 Oct;49(10):e385.
- doi: 10.1038/emm.2017.147
The canonical Wnt pathway is critical for embryonic stem cell (ESC) pluripotency and aberrant control of β-catenin leads to failure of exit from pluripotency and lineage commitments. Hence, maintaining the... -
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- Menin represses JunD transcriptional activity in protein kinase Ctheta-mediated Nur77 expression
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Kim H, Lee JE, Kim BY, Cho EJ, Kim ST, Youn HD
- KMID: 1089456
- Exp Mol Med.
- 2005 Oct;37(5):466-475.
TCR signaling leading to thymocyte apoptosis is mediated through the expression of the Nur77 family of orphan nuclear receptors. It has been shown that the Nur77 promoter is activated by... -
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- A phosphorylation pattern-recognizing antibody specifically reacts to RNA polymerase II bound to exons
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Han J, Lee JH, Park S, Yoon S, Yoon A, Hwang DB, Lee HK, Kim MS, Lee Y, Yang WJ, Youn HD, Kim H, Chung J
- KMID: 2362295
- Exp Mol Med.
- 2016 Nov;48(11):e271.
- doi: 10.1038/emm.2016.101
The C-terminal domain of RNA polymerase II is an unusual series of repeated residues appended to the C-terminus of the largest subunit and serves as a flexible binding scaffold for... -
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