- Why Do We Need Multifunctional Neuroprotective and Neurorestorative Drugs for Parkinson's and Alzheimer's Diseases as Disease Modifying Agents
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Youdim MB
- KMID: 2165314
- Exp Neurobiol.
- 2010 Jun;19(1):1-14.
- doi: 10.5607/en.2010.19.1.1
Parkinson's disease (PD) and Alzheimer's Disease (AD) are severe neurodegenerative disorders, with no drugs that are currently approved to prevent the neuronal cell loss characteristic in brains of patients suffering... -
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- Promise of Neurorestoration and Mitochondrial Biogenesis in Parkinson's Disease with Multi Target Drugs: An Alternative to Stem Cell Therapy
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Youdim MB, Oh YJ
- KMID: 2165480
- Exp Neurobiol.
- 2013 Sep;22(3):167-172.
- doi: 10.5607/en.2013.22.3.167
There is an unmet need in progressive neurodegenerative diseases such as Parkinson's and Alzheimer's diseases. The present therapeutics for these diseases at best is symptomatic and is not able to... -
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- Multi Target Neuroprotective and Neurorestorative Anti-Parkinson and Anti-Alzheimer Drugs Ladostigil and M30 Derived from Rasagiline
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Youdim MB
- KMID: 2165435
- Exp Neurobiol.
- 2013 Mar;22(1):1-10.
- doi: 10.5607/en.2013.22.1.1
Present anti-PD and -AD drugs have limited symptomatic activity and devoid of neuroprotective and neurorestorative property that is needed for disease modifying action. The complex pathology of PD and AD... -
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