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Relations Between IGFBP-3 Promoter Polymorphism and Body Composition Parameters and Obesity

Park JS, Chang YS, Yoo KN, Nam JY, Kim CS, Kim DM, Cho MH, Park J, Ahn CW, Cha BS, Lim SK, Kim KR, Lee HC

  • KMID: 2003331
  • J Korean Soc Study Obes.
  • 2004 Sep;13(3):187-194.
BACKGROUND: Insulin-like growth factor(IGF) binding protein-3(IGFBP-3), which binds to the IGFs in the circulation and acts as a main reservoir of them, regulates their biologic activities either in a IGF...
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Promoter -202 A/C Polymorphism of Insulin-like Growth Factor Binding Protein-3 Gene and Non-small Cell Lung Cancer Risk

Moon JW, Chang YS, Han CH, Kang SM, Park MS, Byun MK, Chung WY, Park JJ, Yoo KN, Shin JH, Kim YS, Chang J, Kim SK, Kim HJ, Kim SK

  • KMID: 2318548
  • Tuberc Respir Dis.
  • 2005 Apr;58(4):359-366.
BACKGROUND: IGFBP-3 inhibits the mitogenic and anti-apoptotic activity of IGF by blocking the binding of IGF to its receptor. However, under certain circumstances, IGFBP- 3 can enhance the activity of...
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