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Clinicopathologic and Biological Parameters Predicting the Prognosis in Endometrial Cancer

Kim JW, Kim SH, Kim YT, Kim DK

Endometrial carcinoma is the most common malignancy of the female genital tract in United States or Europe, but in Korea, its incidence is comparatively low than that of cervical cancer...
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Concurrent Chemoradiotherapy in Cervical Cancer (A New Paradigm in Cervical Cancer Treatment)

Ryu HS

During the last century, the mainstay for the treatment of uterine cervix cancer has been via two main primary treatment modalities, these being radical surgery (radical hysterectomy and regional lymph...
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Screening the High Risk Patient for Gynaecological Cancer

Quinn M

It is often difficult to conclude that improvements in survival with time are due to a screening programme alone. Although a reduction in the death rate from a given cancer...
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Fractionated High-Dose-Rate Brachytherapy in the Management of Uterine Cervical Cancer

Park HC, Suh CO, Kim GE

It is well known that intracavitary radiotherapy (ICR), either alone or in combination with external-beam radiotherapy (EBRT) is an essential component of the radiation treatment of uterine cervical cancer. Although...
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The Application of Human Papillomavirus Testing to Cervical Cancer Screening

Lee HP, Seo SS

Although cytologic screening has considerably reduced the incidence of cervical cancer, there are some problems which remain to be solved, such as the low sensitivity of this procedure. HPV testing...
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Pitfall in Chemotherapy for Ovarian Cancer

Kamura T, Kim YT

Concerning the biological properties of recurrent ovarian cancer, other than drug resistance, we revealed that the expressions of mutant p53 and CD44v6 genes were significantly greater in recurrent ovarian cancer...
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Surgical Management of Recurrent Cervical Cancer

Selman AE, Copeland L

The majority of patients with recurrent cervical cancer are incurable and treatment is based on the type of primary therapy delivered. Only a very small percentage of the patients with...
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Advances in Cervical Cancer Management from North American Cooperative Group Clinical Trials

Berman ML

Despite effective screening methods for detecting pre- malignant diseases of the cervix, cervical cancer remains a leading cause of cancer mortality in women globally. There has been a dramatic decline...
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Alteration of Cell Cycle in Cervical Tumor Associated with Human Papillomavirus: Cyclin-Dependent Kinase Inhibitors

Cho NH, Kim YT, Kim JW

The ability of viral oncoproteins to subvert cell cycle checkpoints may constitute a mechanism by which viral oncoproteins induce genetic instability. HPV 16 E6 and E7 disrupt cell cycle checkpoints,...
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Expression of E-Cadherin and alpha-, beta-, gamma-Catenin Proteins in Endometrial Carcinoma

Kim YT, Choi EK, Kim JW, Kim DK, Kim SH, Yang WI

Loss of the cell adhesion molecule E-cadherin is suggested to promote tumor invasion and distant metastasis in tumor development. Recently, it has been proposed that E-cadherin function requires its linkage...
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Lymph Node Metastasis in a Gynecologic Malignancy

Kamura T, Jeon JD

A radical hysterectomy was performed on patients with stage IA2 to IIB cervical cancer. For these patients, many histopathological parameters have been reported to be prognostic factors of cervical cancer,...
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GSTP1 Polymorphism, Cigarette Smoking and Cervical Cancer Risk in Korean Women

Jee SH, Lee JE, Kim S, Kim JH, Um SJ, Lee SJ, Namkoong S, Park JS

Previous studies have suggested that glutathione S-transferase (GST) genotypes may play a role in determining susceptibility to cervical cancer, though the data have often been conflicting. The objective of this...
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The Comparison of Cytotoxic T-Lymphocyte Effects of Dendritic Cells Stimulated by the Folate Binding Protein Peptide Cultured with IL-15 and IL-2 in Solid Tumor

Kim DK, Kim JH, Kim YT, Kim JW, Ioannides

The current modalities for treating cancer employ not only single but multiple approaches involving surgery, radiotherapy and chemotherapy. Unfortunately, the survival outcome is not promising even with these approaches. Alternative...
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