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Curriculum Design for Problem-Based Learning on a Volunteer Basis: A Yonsei Approach

Kim S, Lee SK, Lee MS, Ahn DS

Innovative new medical programs such as Problem Based Learning (PBL) are being developed worldwide. An increasing number of medical schools are starting to introduce these programs into or even to...
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Incidentally Found Pharyngoesophageal Diverticulum on Ultrasonography

Kim J, Kim YJ, Kim EK, Park CS

The pharyngoesophageal diverticulum in the lower part of the neck can be detected using neck ultrasonography. We present a case of pharyngoesophageal diverticulum mimicking a thyroid nodule, which was found...
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Proteus Syndrome: A Natural Clinical Course of Proteus Syndrome

Linton JA, Seo BK, Oh CS

A 16-year-old Korean male patient presented with macrodactyly, hemihypertrophy of the face and extremities, plantar cerebriform hyperplasia, a subcutaneous mass of the left chest, macrocephaly and verrucous epidermal nevi. These...
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Behavior of Fibroblasts on a Porous Hyaluronic Acid Incorporated Collagen Matrix

Suh H, Lee JE

A hyaluronic acid (HA) incorporated porous collagen matrix was fabricated at -70 degree C by lyophilization. The HA incorporated collagen matrix showed increased pore size in comparison with collagen matrix....
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Descemet's Membrane Detachment Associated with Inadvertent Viscoelastic Injection in Viscocanalostomy

Kim CY, Seong GJ, Koh HJ, Kim EK, Hong YJ

We report a case of Descemet's membrane detachment, a rare complication of viscocanalostomy. During the operation, the injection cannula was directed slightly oblique to the Schlemm's canal rather than parallel...
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Fetal Reduction in Multifetal Pregnancy: Ethical Dilemmas

Tadin I, Roje D, Banovic I, Karelovic , Mimica M

As a result of the increased use of drugs that enhance fertility, and the advent of in vitro fertilization and embryo transfer over the last 2 decades, the incidence of...
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Identification of Tumor Suppressor Loci on the Long Arm of Chromosome 4 in Primary Small Cell Lung Cancers

Cho ES, Chang J, Chung KY, Shin DH, Kim YS, Kim SK, Kim SK

Recent cytogenetic studies have indicated that loss of the long arm of chromosome 4 is a frequent event in small cell lung cancer (SCLC), which suggests the presence of tumor...
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Familial Correlation and Heritability for Cardiovascular Risk Factors

Jee SH, Suh I, Won SY, Kim MY

The goal of this study was to describe the overall genetic contribution of phenotypic variation to cardiovascular disease. The study population included 7,589 family members of 1,891 families, derived from...
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Clinicopathologic Review of Pulmonary Silicone Embolism with Special Emphasis on the Resultant Histologic Diversity in the Lung: A Review of Five Cases

Chung KY, Kim SH, Kwon IH, Choi YS, Noh TW, Kwon TJ, Shin DH

It is known that the subcutaneous injection of silicone can lead to severe pulmonary complications, followed in some patients by respiratory failure. Currently, silicone is being increasingly applied in the...
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Successful Treatment of Pure Red Cell Aplasia with Plasmapheresis in a Patient with Systemic Lupus Erythematosus

Choi BG, Yoo WH

Pure red cell aplasia (PRCA) is a rare cause of anemia associated with systemic lupus erythematosus (SLE), and fewer than 20 cases have been reported. The development of PRCA may...
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Successful Cyclophosphamide Therapy in Recurrent Eosinophilic Colitis Associated with Hypereosinophilic Syndrome

Lee JH, Lee JW, Jang CS, Kwon ES, Min HY, Jeong S, Kwon KS, Lee DH, Cho HG, Kim PS, Kim HG, Shin YW, Kim YS

Eosinophilic colitis is a relatively rare complication of hypereosinophilic syndrome which is characterized by abdominal pain and bloody diarrhea and is usually treated with steroids and hydroxyurea. However, no standard...
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Effect of Ultraviolet Light on the Expression of Adhesion Molecules and T Lymphocyte Adhesion to Human Dermal Microvascular Endothelial Cells

Chung KY, Chang NS, Park YK, Lee KH

In order to determine the effect of ultraviolet radiation (UVR) on the cell adhesion molecules expressed in human dermal microvascular endothelial cells (HDMEC), the cells were exposed to varying UVR...
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Comparative Study of Concentration of Isoflavones and Lignans in Plasma and Prostatic Tissues of Normal Control and Benign Prostatic Hyperplasia

Hong SJ, Kim SI, Kwon SM, Lee JR, Chung BC

Objective: Isoflavones and lignans are phytoestrogens that have recently gained interest as dietary factors related to prostatic diseases. However, no data on the concentrations in prostate tissue in humans is...
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Significance of 99mTc-ECD SPECT in Acute and Subacute Ischemic Stroke: Comparison with MR Images Including Diffusion and Perfusion Weighted Images

Kim HS, Kim DI, Lee JD, Jeong EK, Chung TS, Yoon PH, Lee SK, Kim EJ, Yoon YK, Suh BC, Lee BI

99mTc-ECD SPECT is valuable for the evaluation of cell viability and function. The purpose of the present study was to evaluate the significance of 99mTc-ECD brain SPECT in ischemic stroke....
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Inducible Nitric Oxide Synthase (iNOS) Expression Is Increased in Lipopolysaccharide (LPS)-Stimulated Diabetic Rat Glomeruli: Effect of ACE Inhibitor and Angiotensin II Receptor Blocker

Lee HY, Noh HJ, Gang JG, Xu ZG, Jeong HJ, Kang SW, Choi KH, Han DS

Previously, we reported that high glucose enhanced cytokine-induced nitric oxide (NO) production by rat mesangial cells (MCs), and that the enhanced expression of the iNOS pathway may promote extracellular matrix...
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H2O2 Enhances Ca2+ Release from Osteoblast Internal Stores

Nam SH, Jung SY, Yoo CM, Ahn EH, Suh CK

The physiological activity of osteoblasts is known to be closely related to increased intracellular Ca2+ activity ([Ca2+]i) in osteoblasts. The cellular regulation of [Ca2+]i in osteoblasts is mediated by Ca2+...
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Clinical Significance of Depressed-Type Colorectal Neoplasms Based on Growth and Development

Kim HS, Lee JK, Lee JD, Kim KY

A route of colorectal cancer development other than the adenoma-carcinoma sequence has recently become an issue due to the discovery of depressed-type early colorectal cancers. Moreover, the fact that some...
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Therapeutic Outcome of Epstein-Barr Virus Positive T/NK Cell Lymphoma in the Upper Aerodigestive Tract

Hahn JS, Lee ST, Min YH, Ko YW, Yang WI, Kim GE

Expression of the natural killer (NK) cell antigen CD56 is uncommon in malignant lymphoma, but when it is, it is almost exclusively of the non-B cell lineage and show a...
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Autoantibody against, Malondialdehyde-Modified Low Density Lipoprotein in Patients with Non-Diabetic Unstable Angina: A Potential Role in Immunologic Reaction of Plaque Instability

Kwon KH, Kwon HM, Hong BK, Kim DS, Lee JY, Ryu SK, Park BE, Park HY, Kim JH, Yoon YW, Cho SY, Kim HS

The role of autoantibody against oxidized low-density lipoprotein (LDL) in the pathogenesis of atherosclerosis is still unknown. The purpose of this study was to determine whether autoantibodies against malondialdehyde (MDA)-modified...
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Local Delivery of Nitric Oxide from an Eluting Stent to Inhibit Neointimal Thickening in a Porcine Coronary Injury Model

Yoon JH, Wu CJ, Homme J, Tuch RJ, Wolff RG, Topol EJ, Lincoff AM

To assess the effect of a NO-eluting stent on reducing neointimal thickening in a porcine coronary artery stent injury model, sodium nitroprusside (SNP), a NO donor, was incorporated into polyurethane...
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