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The First Case of Familial Mediterranean Fever Associated with Renal Amyloidosis in Korea

Koo KY, Park SJ, Wang JY, Shin JI, Jeong HJ, Lim BJ, Lee JS

Familial Mediterranean fever (FMF) is an auto-inflammatory disease characterized by periodic episodes of fever and recurrent polyserositis. It is caused by a dysfunction of pyrin (or marenostrin) as a result...
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Antimicrobial Susceptibility of Stenotrophomonas maltophilia Isolates from a Korean Tertiary Care Hospital

Chung HS, Hong SG, Lee Y, Kim M, Yong D, Jeong SH, Lee K, Chong Y

We determined the antimicrobial susceptibility of 90 clinical isolates of Stenotrophomonas maltophilia collected in 2009 at a tertiary care hospital in Korea. Trimethoprim-sulfamethoxazole, minocycline, and levofloxacin were active against most...
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Identification of Vulnerable Plaque in a Stented Coronary Segment 17 Years after Implantation Using Optical Coherence Tomography

Yang JH, Byeon K, Gwon HC, Park JE, Song YB

A patient presented with exertional chest pain two months prior to admission. Coronary angiography revealed a subocclusive stenosis within the boundaries of the stent. Optical coherence tomography showed remarkable intimal...
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Transumbilical Single Port Laparoscopic Adrenalectomy: A Technical Report on Right and Left Adrenalectomy Using the Glove Port

Choi SH, Hwang HK, Kang CM, Lee WJ

Recently, single port laparoscopic surgery has been the focus of attention due to the advanced laparoscopic skills accumulated from experience and developments in laparoscopic instruments. Herein, we present two cases...
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Treatment Outcome of Patients with Anaplastic Thyroid Cancer: A Single Center Experience

Lim SM, Shin SJ, Chung WY, Park CS, Nam KH, Kang SW, Keum KC, Kim JH, Cho JY, Hong YK, Cho BC

PURPOSE: Anaplastic thyroid cancer is known to have a poor prognosis due to its aggressive and rapid metastasis with median survival of less than 6 months. Multimodal treatment involving surgery...
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Current Management and Future Strategies of Gastric Cancer

Lee JH, Kim KM, Cheong JH, Noh SH

The overall prognosis of gastric cancer has gradually improved over the past decades with growing awareness of potential carcinogens, surveillance programs and early diagnosis, as well as advances in surgical...
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Sequential Involvement of the Nervous System in Subacute Combined Degeneration

Minn YK, Kim SM, Kim SH, Kwon KH, Sunwoo IN

PURPOSE: Subacute combined degeneration (SCD) involves progressive degeneration of the spinal cord, optic nerve, and peripheral nerves. Vitamin B12 (VB12) is a co-factor in myelin synthesis. Because each cell that...
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A Case of Acute Polyneuropathy with Nephrotic Syndrome Showing Transient Proximal Sensory Conduction Defects

Oh J, Kim SM, Sunwoo IN

Acute sensorimotor polyneuropathy that resembles Guillain-Barre syndrome (GBS) is rarely accompanied with nephrotic syndrome, and its underlying immunological mechanisms are unclear. A 56-year-old man presented with simultaneous acute progressive symmetric...
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Autophagy in Innate Recognition of Pathogens and Adaptive Immunity

Oh JE, Lee HK

Autophagy is a specialized cellular pathway involved in maintaining homeostasis by degrading long-lived cellular proteins and organelles. Recent studies have demonstrated that autophagy is utilized by immune systems to protect...
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Are Clinically Insignificant Prostate Cancers Really Insignificant among Korean Men?

Yeom CD, Lee SH, Park KK, Park SU, Chung BH

PURPOSE: We aimed to determine whether 12 core-extended biopsies of the prostate could predict insignificant prostate cancer (IPCa) in Koreans reliably enough to recommend active surveillance. MATERIALS AND METHODS: Two hundred...
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Treatment of Femoral Shaft Fracture with an Interlocking Humeral Nail in Older Children and Adolescents

Park H, Kim HW

PURPOSE: Rigid interlocking nailing for femoral shaft fracture is ideal for use in adolescents in terms of stability of the fracture and convenience for the patient. However, numerous authors have...
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Spontaneous Bacterial Peritonitis in Patients with Hepatitis B Virus-Related Liver Cirrhosis: Community-Acquired versus Nosocomial

Kim SU, Chon YE, Lee CK, Park JY, Kim DY, Han KH, Chon CY, Kim S, Jung KS, Ahn SH

PURPOSE: Spontaneous bacterial peritonitis (SBP) frequently develops in patients with liver cirrhosis; however, there is little data to suggest whether the acquisition site of infection influences the prognosis. This study...
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Endoscopist Specialty Is Associated with High-Quality Endoscopy in Korea

Cha JM, Han DS, Lee HL, Kim YH, Chung IK, Kim HS, Moon JS, Cho YK

PURPOSE: The present study was aimed to determine whether endoscopist specialty is associated with high-quality endoscopy. MATERIALS AND METHODS: We prospectively collected endoscopy quality related data based on the Endoscopy Quality...
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How Many Valid Measurements Are Necessary to Assess Liver Fibrosis Using FibroScan(R) in Patients with Chronic Viral Hepatitis? An Analysis of Subjects with at Least 10 Valid Measurements

Jang HW, Kim SU, Park JY, Ahn SH, Han KH, Chon CY, Park YN, Choi EH, Kim DY

PURPOSE: Using FibroScan(R) to obtain a reliable liver stiffness measurement (LSM) may require more than 10 valid measurements (VMs), according to the manufacturer's recommendations. However, this requirement lacks scientific evidence...
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Role of Inflammation in the Pathogenesis of Arterial Stiffness

Park S, Lakatta EG

Increased arterial stiffness is an independent predictor of cardiovascular disease independent from blood pressure. Recent studies have shed new light on the importance of inflammation on the pathogenesis of arterial...
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Acute Variceal Hemorrhage in Patients with Liver Cirrhosis: Weekend versus Weekday Admissions

Byun SJ, Kim SU, Park JY, Kim BK, Kim DY, Han KH, Chon CY, Ahn SH

PURPOSE: Little is known about the impact of weekend admission on acute variceal hemorrhage (AVH). Thus, we investigated whether day of admission due to AVH influenced in-hospital mortality. MATERIALS AND METHODS:...
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The Box Simulator Is Useful for Training Novice Endoscopists in Basic Endoscopic Techniques

Cha JM, Lee JI, Joo KR, Shin HP, Park JJ, Jeon JW, Lim JU, Lym K

PURPOSE: The present study was aimed at evaluating the usefulness of box simulators for training novice endoscopists. MATERIALS AND METHODS: An explanation of the goals, contents, and features of the simulator...
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Electroanatomical Characteristics of Idiopathic Left Ventricular Tachycardia and Optimal Ablation Target during Sinus Rhythm: Significance of Preferential Conduction through Purkinje Fibers

Park J, Kim YH, Hwang C, Pak HN

PURPOSE: We hypothesized that Purkinje potential and their preferential conduction to the left ventricle (LV) posteroseptum during sinus rhythm (SR) are part of reentrant circuits of idiopathic left ventricular tachycardia...
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Herpes Simplex Virus 2 Infection Rate and Necessity of Screening during Pregnancy: A Clinical and Seroepidemiologic Study

Kim ID, Chang HS, Hwang KJ

PURPOSE: This study determined the seroprevalence of herpes virus 2 in gravidas and the differences between herpes virus 2-infected and healthy gravidas. The need to screen gravidas for herpes virus...
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Serum Vascular Endothelial Growth Factor and Angiopoietin-2 Are Associated with the Severity of Systemic Inflammation Rather than the Presence of Hemoptysis in Patients with Inflammatory Lung Disease

Park HY, Hahm CR, Jeon K, Koh WJ, Suh GY, Chung MP, Kim H, Kwon OJ, Um SW

PURPOSE: Vascular endothelial growth factor (VEGF) and angiopoietin-2 (Ang-2) are major mediators of angiogenesis and are induced by tissue inflammation and hypoxia. The purpose of this study was to investigate...
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