- Effect of Clonidine on the Pharmacodynamics and Recovery of Bupivacaine Neural Blockade
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Kil HY, Glass PS
- KMID: 2298879
- Korean J Anesthesiol.
- 1994 Sep;27(9):1053-1060.
- doi: 10.4097/kjae.1994.27.9.1053
No abstract available. -
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- The Effects of Yohimbine + Trazodone or Yohimbine + Isoxsuprine on Recovery of Potency in Psychogenic and/or Arteriogenic Impotent Patients
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Choi DY, Lee YE, Kim SC
- KMID: 1960429
- J Korean Androl Soc.
- 1990 Jun;8(1):31-36.
Yohimbine is a presynaptic alpha-2 receptor blocker that decreases outflow of blood from the corporeal tissue. It also probably works on upper levels in the brain to increase libido with... -
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- A study of alpha adrenergic receptors in human and rabbit corpus cavernosum tissue
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Park KH, Paick JS, Kim MS
- KMID: 2139511
- Korean J Urol.
- 1993 Apr;34(2):345-352.
The relaxation of the corpus cavernosum smooth muscle, which is main process in penile erection, is controlled by nerves that release cholinergic and nonadrenergic-noncholinergic neurotransmitters as well as vascular endothelium... -
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- Effects of Clonidine and Yohimbine on Neuropathic Pain in a Rat Model
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Yang JH, Song EB, Kim SJ, Lee SH, Na HS
- KMID: 2323478
- J Korean Acad Rehabil Med.
- 2000 Aug;24(4):587-593.
OBJECTIVE: In a rat model of peripheral neuropathy, to determine whether neuropathic pain is related to the alpha-2 adrenergic receptor. METHOD: The neuropathic pain was produced by unilateral transection of the... -
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- Effect of Anxiogenic Drug on Stress Reaction Induced by Conflict
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Park YS
- KMID: 1965006
- Ewha Med J.
- 1994 Jun;17(2):93-101.
- doi: 10.12771/emj.1994.17.2.93
In this experiment, examined were short-term effect of alpha-2 adrenoreceptor agonist yohimbine on physiological, behavioral changes and ulceration induced by the 48 hr. conflict-stress session and compared with effect of... -
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- Effects of Various alpha-Adrenoceptor Antagonists on Pressor Responses to Norepinephrine and Phenylephrine
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Song HS
- KMID: 2239618
- Korean J Anesthesiol.
- 1983 Mar;16(1):7-13.
1) The effects of various alpha-adrenoceptor antagonists on the pressor responses to norepinephrine and phenylephrine were examined in anesthetized rabbits in an attempt to determine whether alpha1 and alpha2-adrenoceptors are... -
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- Studies on Bradycardiac Effect of Methoxamine in Rabbits
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Chung SS, Ha IH
- KMID: 1933288
- Korean J Anesthesiol.
- 1987 Jun;20(3):341-348.
- doi: 10.4097/kjae.1987.20.3.341
The bradycardiac and presor to intravenous and intraventricular methoxamine were examined in urethane-anesthetized rabbits 1) Intravenous methoxamine produced bradycardiac pressor responses. Atropine (2 mg/kg, i,v.) weakened but not abloished... -
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- Do Presynaptic alpha-Adrenoceptors Exist in the Cardioaccelerator Nerve of Cold-blooded Animals?
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Ko BS, Ha IH
- KMID: 2357406
- Korean J Anesthesiol.
- 1981 Mar;14(1):6-13.
1) The author investigated whether presynaptic alpha-adrenoceptors exist in the cardioaccelerator nerves of cold-blooded animals(frog, tortoise) as in ones of in mammals. 2) Each atrial preparation of a frog, tortoise... -
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- Antinociceptive Effects of Tramadol on the Neuropathic Pain in Rats
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Song KW, Kim HJ, Yum KW
- KMID: 2335946
- J Korean Pain Soc.
- 2001 Dec;14(2):150-155.
BACKGROUND: Tramadol is known to be a weak opioid. However, it has also been shown that tramadol is an effective norepinephrine and serotonin uptake blocker, which may be effective in... -
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- Effect of Alpha-2 Receptor Blocker on Serotonin Release in Rat Hippocampal Slices
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Song YS, Kim ME, Park YH, Ahn YS
- KMID: 1573711
- Korean J Androl.
- 2000 Aug;18(2):111-115.
PURPOSE: It is known that alpha-2 receptor is found at the presynaptic serotonergic nervous system and a consequence of increased activation of alpha-2 receptor decreases the serotonin release. So Alpha-2... -
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- Central Hypotensive Effects of Imipramine in Anesthetized Rats
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Yoon PJ, Chio HS, Yeum CH
- KMID: 1894902
- Korean Circ J.
- 1992 Oct;22(5):825-830.
- doi: 10.4070/kcj.1992.22.5.825
BACKGROUND: One of prominent cardiovascular effects of imipramine is postural hypotension. The present study was to verify whether imipramine has a central hypotensive action and futher to investigate its mechanism... -
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- Differences between Physostigmine- and Yohimbine-induced States Are Visualized in Canonical Space Constructed from EEG during Natural Sleep-wake Cycle in Rats
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Lee MG, Kim M, Roh M, Jang IS, Won SH
- KMID: 2165347
- Exp Neurobiol.
- 2011 Mar;20(1):54-65.
- doi: 10.5607/en.2011.20.1.54
Although quantitative EEG parameters, such as spectral band powers, are sensitive to centrally acting drugs in dose- and time-related manners, changes of the EEG parameters are redundant. It is desirable... -
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- The Role of Adrenergic and Cholinergic Receptors on the Antinociception of Intrathecal Zaprinast in the Formalin Test of Rats
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Yoon SJ, Kim YO, Huang LJ, Cui JH, Heo BH, Jeong ST, Yoon MH
- KMID: 2238303
- Korean J Anesthesiol.
- 2007 Jul;53(1):85-90.
- doi: 10.4097/kjae.2007.53.1.85
BACKGROUND: Spinal zaprinast, phospodiesterase inhibitor, has been shown to have an antinociception through an increase of cGMP. The aim of this study was to examine the role of spinal adrenergic... -
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- Dexmedetomidine Preconditioning Attenuates Cisplatin-Induced Ototoxicity in Zebrafish
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Min TJ, Kim WY, Ha YR, Jeong IY, Yoo JY
- KMID: 2278367
- Clin Exp Otorhinolaryngol.
- 2014 Dec;7(4):275-280.
- doi: 10.3342/ceo.2014.7.4.275
OBJECTIVES: Utilisation of high-frequency drills is known to increase noise induced hearing loss due to increasing the damages of inner ear cells. This study aimed to investigate whether preconditioning by... -
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- The Antinociceptive and Antiallodynic Effects by Brimonidine, a Selective alpha2 Adrenergic Agonist
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Park JY, Park JH, Hwang JH
- KMID: 2236811
- Korean J Anesthesiol.
- 2001 Mar;40(3):397-405.
- doi: 10.4097/kjae.2001.40.3.397
BACKGROUND: Clonidine, an alpha2 adrenoceptor agonist, has been known to have antinociceptive and antiallodynic effects. The antinociceptive and antiallodynic effects of brimonidine, a new selective alpha2 agonist, have not... -
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- The Effect of alpha2 Adrenoceptors and Imidazoline Receptors on the Mechanical Allodynia in Rats with Nerve Ligation Injury
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Hwang JH, Kim YK, Park JY, Jun HJ
- KMID: 2236831
- Korean J Anesthesiol.
- 2001 Feb;40(2):252-260.
- doi: 10.4097/kjae.2001.40.2.252
BACKGROUND: Clonidine, an alpha2 adrenoceptor agonist, has been known to have an antiallodynic effect in many animal and human studies. Clonidine, however, acts on imidazoline receptors as well as... -
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- Effect of Spinal Adrenergic and Cholinergic Antagonists for Antinociception of Intrathecal Gabapentin
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Yoon MH, Chung SS, Kim HS
- KMID: 2091695
- Korean J Anesthesiol.
- 2002 May;42(5):677-684.
- doi: 10.4097/kjae.2002.42.5.677
BACKGROUND: Intrathecal gabapentin is effective on nociceptive states evoked by tissue injury. In addition, gabapentin interacts synergistically with clonidine at the spinal level, suggesting that a mechanism of gabapentin... -
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- Anxiolytic Action of Taurine via Intranasal Administration in Mice
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Jung JH, Kim SJ
- KMID: 2456219
- Biomol Ther.
- 2019 Sep;27(5):450-456.
- doi: 10.4062/biomolther.2018.218
Taurine has a number of beneficial pharmacological actions in the brain such as anxiolytic and neuroprotective actions. We explored to test whether taurine could be transported to the central nervous... -
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- The Role of Adrenergic and Cholinergic Receptors on the Antinociception of Korean Red Ginseng in the Spinal Cord of Rats
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Kim SY, Yoon MH, Lee HG, Kim WM, Lee JD, Kim YO, Huang LJ, Cui JH
- KMID: 1480642
- Korean J Pain.
- 2008 Apr;21(1):27-32.
- doi: 10.3344/kjp.2008.21.1.27
BACKGROUND: Experimental evidence indicates that ginseng modulate the nociceptive transmission. Authors examined the role of adrenergic and cholinergic receptors on the antinociceptive action of Korean red ginseng against the formalin-induced... -
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- Monoaminergic Activity by Drugs Acting on Adrenergic alpha2-receptors in Rat Hippocampus and Primary Visual Cortex
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Kim HG, Lee YC, Paik KC, Lim MH, Kim HW, Kang BJ
- KMID: 2286867
- Korean J Psychopharmacol.
- 2004 Sep;15(3):371-379.
OBJECTIVE: The aim of the this study was to compare the effects of clonidine (a alpha2-adrenoceptor and imidazoline receptor agonist), yohimbine (a selective alpha2-adrenoceptor antagonist) and idazoxan (a alpha2-adrenoceptor and... -
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