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Cytotoxic Activity and Quantitative Structure Activity Relationships of Arylpropyl Sulfonamides

Hwang YJ, Park SM, Yim CB, Im C

B13 is a ceramide analogue and apoptosis inducer with potent cytotoxic activity. A series of arylpropyl sulfonamide analogues of B13 were evaluated for their cytotoxicity using MTT assays in prostate...
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Cytotoxic Activity and Structure Activity Relationship of Ceramide Analogues in Caki-2 and HL-60 Cells

Kim YJ, Kim EA, Sohn UD, Yim CB, Im C

B13, a ceramide analogue, is a ceramidase inhibitor and induces apoptosis to give potent anticancer activity. A series of thiourea B13 analogues was evaluated for their in vitro cytotoxic activities...
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