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The immune modulating properties of the heat shock proteins after brain injury

Kim JY, Yenari MA

Inflammation within the central nervous system often accompanies ischemia, trauma, infection, and other neuronal injuries. The immune system is now recognized to play a major role in neuronal cell death...
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Direct protection of cultured neurons from ischemia-like injury by minocycline

Huang WC, Qiao Y, Xu L, Kacimi R, Sun X, Giffard RG, Yenari MA

Minocycline, a tetracycline antibiotic, is now known to protect cells via an anti-inflammatory mechanism. We further explored this effect using an in vitro model of ischemia-like injury to neurons. Coculturing...
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NOX Inhibitors - A Promising Avenue for Ischemic Stroke

Kim JY, Park J, Lee JE, Yenari MA

NADPH-oxidase (NOX) mediated superoxide originally found on leukocytes, but now recognized in several types of cells in the brain. It has been shown to play an important role in the...
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