- Auranofin Suppresses Plasminogen Activator Inhibitor-2 Expression through Annexin A5 Induction in Human Prostate Cancer Cells
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Shin DW, Kwon YJ, Ye DJ, Baek HS, Lee JE, Chun YJ
- KMID: 2375038
- Biomol Ther.
- 2017 Mar;25(2):177-185.
- doi: 10.4062/biomolther.2016.223
Auranofin has been developed as antirheumatic drugs, which is currently under clinical development for the treatment of chronic lymphocytic leukemia. Previous report showed that auranofin induced apoptosis by enhancement of... -
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- Annexin A5 as a New Potential Biomarker for Cisplatin-Induced Toxicity in Human Kidney Epithelial Cells
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Kwon YJ, Jung JJ, Park NH, Ye DJ, Kim D, Moon A, Chun YJ
- KMID: 1502486
- Biomol Ther.
- 2013 May;21(3):190-195.
Cisplatin is a member of platinum-containing anti-cancer drugs that causes cross-linking of DNA and ultimately cancer cell apoptosis. The therapeutic function of cisplatin on various types of cancers has been... -
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- Induction of Integrin Signaling by Steroid Sulfatase in Human Cervical Cancer Cells
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Ye DJ, Kwon YJ, Shin S, Baek HS, Shin DW, Chun YJ
- KMID: 2378811
- Biomol Ther.
- 2017 May;25(3):321-328.
- doi: 10.4062/biomolther.2016.155
Steroid sulfatase (STS) is an enzyme responsible for the hydrolysis of aryl and alkyl sulfates. STS plays a pivotal role in the regulation of estrogens and androgens that promote the... -
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- G0/G1 Switch 2 Induces Cell Survival and Metastasis through Integrin-Mediated Signal Transduction in Human Invasive Breast Cancer Cells
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Cho E, Kwon YJ, Ye DJ, Baek HS, Kwon TU, Choi HK, Chun YJ
- KMID: 2462887
- Biomol Ther.
- 2019 Nov;27(6):591-602.
- doi: 10.4062/biomolther.2019.063
Human breast cancer cell line, MDA-MB-231, is highly invasive and aggressive, compared to less invasive cell line, MCF-7. To explore the genes that might influence the malignancy of MDA-MB-231, DNA... -
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