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A Case of Nasu-Hakola Disease without Fractures or Consanguinity Diagnosed Using Exome Sequencing and Treated with Sodium Valproate

Yamazaki K, Yoshino Y, Mori Y, Ochi S, Yoshida T, Ishimaru T, Ueno SI

Nasu-Hakola disease (NHD) is a rare autosomal recessive neuropsychiatric disorder characterized by bone cysts, fractures, and cognitive impairment. Two genes are responsible for the development of NHD; TYROBP and TREM2....
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Partially unroofed coronary sinus with persistent left superior vena cava: the utility of two and three-dimensional transesophageal echocardiography: a case report

Yonekura H, Kanazawa S, Miyawaki I, Yamazaki K

Unroofed coronary sinus (URCS) is a rare cardiac anomaly, in which communication occurs between the coronary sinus (CS) and the left atrium (LA) because of partial or complete absence of...
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Combination Therapy with Rituximab and Temozolomide for Recurrent and Refractory Primary Central Nervous System Lymphoma

Murakami M, Fujimaki T, Asano S, Nakaguchi , Yamada SM, Hoya K, Yamazaki K, Ishida Y, Matsuno A

High-dose methotrexate-based chemotherapy has extended survival in patients with primary central nervous system lymphoma (PCNSL). However, although salvage treatment is necessary in recurrent and refractory PCNSL, this has not been...
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Appropriate Tensile Mode and Timing of Applying Tension to Promote Tendon Gel Regeneration

Kuzumaki T, Yamazaki K, Suzuki K, Torigoe K

“Tendon gel” secreted from a parent tendon is regenerated for tendon repair by applying tension. However, the details of the tensile stimulus have not been clarified. This study aimed to...
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Efficacy of Two-Stage Surgery for Spinal Cord Ependymomas

Takamiya S, Seki T, Yamazaki K, Yano S, Hida K

Study Design: Retrospective cohort study. Purpose: This study aimed to elucidate cases for which staged surgeries are effective by a retrospective review of previous operative cases of spinal ependymomas. Overview of Literature:...
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Undiagnosed Peripheral Nerve Disease in Patients with Failed Lumbar Disc Surgery

Yamauchi T, Kim K, Isu T, Iwamoto N, Yamazaki K, Matsumoto , Isobe M

STUDY DESIGN: Retrospective study (level of evidence=3). PURPOSE: We examine the relationship between residual symptoms after discectomy for lumbar disc herniation and peripheral nerve (PN) neuropathy. OVERVIEW OF LITERATURE: Patients may report...
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