- RBP2 induces stem-like cancer cells by promoting EMT and is a prognostic marker for renal cell carcinoma
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Zhou D, Kannappan , Chen X, Li J, Leng X, Zhang J, Xuan S
- KMID: 2361525
- Exp Mol Med.
- 2016 Jun;48(6):e238.
- doi: 10.1038/emm.2016.37
Renal cell carcinoma (RCC), one of the most common kidney cancers, has a poor prognosis. Epithelial to mesenchymal transition (EMT) is a hallmark of carcinoma invasion and metastasis. Several studies... -
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- TM6SF2 E167K variant decreases PNPLA3-mediated PUFA transfer to promote hepatic steatosis and injury in MASLD
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Sun B, Ding X, Tan J, Zhang J, Chu X, Zhang S, Liu S, Zhao Z, Xuan S, Xin Y, Zhuang L
- KMID: 2560090
- Clin Mol Hepatol.
- 2024 Oct;30(4):863-882.
- doi: 10.3350/cmh.2024.0268
Backgrounds/Aims: Transmembrane 6 superfamily member 2 (TM6SF2) E167K variant is closely associated with the occurrence and development of metabolic dysfunction-associated steatotic liver disease (MASLD). However, the role and mechanism of... -
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