- Angiotensin II Receptor Blocker Induced Inhibition of Cellular Hypertrophy and Differential Expression of Cyclin-dependent Kinase Inhibitors in Cultured Podocytes Stimulated by Long-term High Glucose
-
Park HC, Xu ZG, Ryu DR, Yoo TH, Jung DS, Kim JJ, Kwak SJ, Li JJ, Kang SW
- KMID: 1337394
- Korean J Nephrol.
- 2006 Sep;25(5):695-704.
BACKGROUND: Hypertrophy of podocytes is observed in type 2 diabetic patients. Cellular hypertrophy requires combined effects of various mitogen- induced entry into the cell cycle and subsequent cell cycle arrest... -
- CITED
-
- Close
- SHARE
-
- Close
- The Effect of High Glucose on Renin-Angiotensin System (RAS) in Podocytes
-
Yoo TH, Ryu DR, Lee JJ, Kim JJ, Jung DS, Kwak SJ, Xu ZG, Kim JS, Kim HJ, Choi HY, Han DS, Kang SW
- KMID: 1867693
- Korean J Nephrol.
- 2006 Nov;25(6):903-912.
The renin-angiotensin system (RAS) plays an important role in the pathogenesis of diabetic nephropathy. Recently, the activation of local RAS in mesangial cells by high glucose has been reported. However,... -
- CITED
-
- Close
- SHARE
-
- Close
- P-Cadherin is Decreased in Glucose-Stimulated Podocytes and in Experimental Diabetic Nephropathy
-
Ryu DR, Xu ZG, Yoo TH, Chang JH, Jung DS, Lee SH, Kim JJ, Choi KH, Lee HY, Han DS, Kang SW
- KMID: 2079302
- Korean J Nephrol.
- 2003 Sep;22(5):494-503.
BACKGROUND: Proteinuria is a cardinal feature of glomerular disease including diabetic nephropathy, and glomerular filtration barrier is considered as a filter restricting protein excretion in urine. We tested whether the... -
- CITED
-
- Close
- SHARE
-
- Close
- Inducible Nitric Oxide Synthase (iNOS) Expression Is Increased in Lipopolysaccharide (LPS)-Stimulated Diabetic Rat Glomeruli: Effect of ACE Inhibitor and Angiotensin II Receptor Blocker
-
Lee HY, Noh HJ, Gang JG, Xu ZG, Jeong HJ, Kang SW, Choi KH, Han DS
- KMID: 1118967
- Yonsei Med J.
- 2002 Apr;43(2):183-192.
- doi: 10.3349/ymj.2002.43.2.183
Previously, we reported that high glucose enhanced cytokine-induced nitric oxide (NO) production by rat mesangial cells (MCs), and that the enhanced expression of the iNOS pathway may promote extracellular matrix... -
- CITED
-
- Close
- SHARE
-
- Close
- The Effect of High Glucose on p38 MAPK Pathway and Fibronectin Synthesis in Cultured Rat Mesangial Cells
-
Yoo TH, Xu ZG, Ryu DR, Kim HW, Lee SH, Kim JJ, Jung DS, Choi KH, Lee HY, Han DS, Kang SW
- KMID: 2079301
- Korean J Nephrol.
- 2003 Sep;22(5):483-493.
BACKGROUND: The p38 mitogen-activated protein kinase (MAPK) pathway is activated by several stress factors, potentially leading to cellular apoptosis and growth. Little is known about the pattern of p38 MAPK... -
- CITED
-
- Close
- SHARE
-
- Close
- The Effect of Pioglitazone on the Expression of Transforming Growth Factor (TGF)-beta and Fibronectin in Diabetic Nephropathy
-
Yoon SY, Xu ZG, Ryu DR, Cha BS, Kang SW, Choi KH, Lee HY, Han DS
- KMID: 2079623
- Korean J Nephrol.
- 2006 May;25(3):353-364.
BACKGROUND: Peroxisome proliferator-activated receptor (PPAR)-gamma is a member of the nuclear receptor superfamily. PPAR-gamma plays an important role in numerous cellular processes including adipogenesis, insulin sensitivity, cell cycle progression, cell... -
- CITED
-
- Close
- SHARE
-
- Close
- Changes of ZO-1 Expression in Diabetic Rat Glomeruli and Cultured Mouse Podocyte Under High Glucose Conditions and the Effect of Angiotensin II Type 1 Receptor Blocker
-
Kim BS, Xu ZG, Park HC, Kang SW, Choi KH, Ha SK, Lee HY, Han DS
- KMID: 2079346
- Korean J Nephrol.
- 2003 Nov;22(6):632-644.
BACKGROUND: Diabetic nephropathy (DN) is clinically characterized by persistent proteinuria. The underlying pathologic changes responsible for the nephropathy are the loss of size selective and/or charge selective properties of the... -
- CITED
-
- Close
- SHARE
-
- Close
- The Effect of ACE Gene Polymophism on the Antiproteinuric Effect of Angiotensin II Receptor Antagonist in Patients with Non-diabetic Chronic Renal Disease
-
Choi HY, Xu ZG, Kim HW, Kim HJ, Kim HJ, Kim BS, Park HC, Kang SW, Choi KH, Ha SK, Lee HY, Han DS
- KMID: 1989565
- Korean J Nephrol.
- 2004 Jan;23(1):46-56.
BACKGROUND: Angiotensin II, a potent vasoconstrictor, plays a key role in renal injury and in the progression of chronic renal disease of diverse causes. In every organ system, the biologic... -
- CITED
-
- Close
- SHARE
-
- Close
