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Protein Kinase C Mediates the Corticosterone-induced Sensitization of Dorsal Root Ganglion Neurons Innervating the Rat Stomach

Li M, Xue L, Zhu HY, Wang H, Xu X, Zhang PA, Wu G, Xu GY

  • KMID: 2387838
  • J Neurogastroenterol Motil.
  • 2017 Jul;23(3):464-476.
  • doi: 10.5056/jnm16161
BACKGROUND/AIMS: Gastric hypersensitivity contributes to abdominal pain in patients with functional dyspepsia. Recent studies showed that hormones induced by stress are correlated with visceral hypersensitivity. However, the precise mechanisms underlying...
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The Relationship Between Preoperative Cervical Sagittal Balance and Clinical Outcome of Patients With Hirayama Disease Treated With Anterior Cervical Discectomy and Fusion

Lu X, Xu GY, Nie C, Zhang YX, Song J, Jiang JY

Objective: Anterior cervical discectomy and fusion (ACDF) is a common surgical method used to treat patients with Hirayama disease. And sagittal balance indexes have been revealed to be predictors of...
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Acute Effects of Transforming Growth Factor-β1 on Neuronal Excitability and Involvement in the Pain of Rats with Chronic Pancreatitis

Zhang X, Zheng H, Zhu HY, Hu S, Wang S, Jiang X, Xu GY

  • KMID: 2203587
  • J Neurogastroenterol Motil.
  • 2016 Apr;22(2):333-343.
  • doi: 10.5056/jnm15127
BACKGROUND/AIMS: This study was to investigate whether transforming growth factor-β1 (TGF-β1) plays a role in hyperalgesia in chronic pancreatitis (CP) and the underlying mechanisms. METHODS: CP was induced in male adult...
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Colonic Hypersensitivity and Sensitization of Voltage-gated Sodium Channels in Primary Sensory Neurons in Rats with Diabetes

Hu J, Song ZY, Zhang HH, Qin X, Hu S, Jiang X, Xu GY

  • KMID: 2379712
  • J Neurogastroenterol Motil.
  • 2016 Jan;22(1):129-140.
  • doi: 10.5056/jnm15091
BACKGROUND/AIMS: Patients with long-standing diabetes often demonstrate intestinal dysfunction and abdominal pain. However, the pathophysiology of abdominal pain in diabetic patients remains elusive. The purpose of study was to determine...
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