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Modulation by aspartate of ischemia/reperfusion-induced oxidative stress in rat liver

Park YC, Oh SI, Park YH, Park SC

  • KMID: 2128621
  • Exp Mol Med.
  • 1997 Mar;29(1):19-23.
Ischemia-reperfusion injury is related with oxygen free radicals; a reason which has been suggested for this is the conversion of xanthine dehydrogenase (XDH) into xanthine oxidase (XO). In the present...
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Change of Plasma Xanthine Oxidase Activity by Intermittent Hepatic Ischemia-Reperfusion

Ha SJ, Kim JH, Park SS, Kim I, Baek W, Lim DG

BACKGROUND: The pringle maneuver (PM), hepatic inflow occlusion, during hepatic surgery reduces intraoperative bleeding and blood transfusion requirement, but hepatic ischemia/reperfusion injury is inevitable. During ischemia, xanthine oxidoreductase is converted...
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Effects of Supplementation with a Selective COX-2 Inhibitor and Vitamin C on Glomerular TGF-beta, COX-2, and Antioxidant Activity in Rats with Passive Heymann Nephritis

Jung YS, Rim H, Moon W, Choi J, Sol MY

  • KMID: 2253156
  • Korean J Nephrol.
  • 2009 Sep;28(5):397-409.
PURPOSE: In the passive Heymann nephritis (PHN) rat model of membranous nephropathy, complement induces glomerular epithelial cell injury and proteinuria, which is partially mediated by reactive oxygen species (ROS), TGF-beta,...
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