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The Intracisternal Administration of MEK Inhibitor Attenuates Mechanical and Cold Allodynia in a Rat Model of Compression of the Trigeminal Ganglion

Lee MK, Yoon JH, Park MK, Yang GY, Won KA, Park YY, Ahn DK

  • KMID: 1457179
  • Int J Oral Biol.
  • 2010 Sep;35(3):75-81.
The present study investigated the role of ERK in the onset of mechanical and cold allodynia in a rat model of compression of the trigeminal ganglion by examining changes in...
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Intracisternal Administration of Voltage Dependent Calcium Channel Blockers Attenuates Orofacial Inflammatory Nociceptive Behavior in Rats

Won KA, Park SH, Kim BK, Baek KS, Yoon DH, Ahn DK

  • KMID: 2170724
  • Int J Oral Biol.
  • 2011 Jun;36(2):43-50.
Voltage dependent calcium channel (VDCC), one of the most important regulator of Ca2+ concentration in neuron, play an essential role in the central processing of nociceptive information. The present study...
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A Blockade of the Central MAPK Pathway Attenuates Referred Pain in Rats with Complete Freund's Adjuvant-Induced Inflammation of the Temporomandibular Joint

Won KA, Lim NH, Lee MK, Park MK, Yang GY, Park YY, Ahn DK, Bae YC

  • KMID: 1457180
  • Int J Oral Biol.
  • 2010 Sep;35(3):83-89.
We investigated the role of the central MAPK pathways in extra-territorial (referred) pain resulting from inflammation of the temporomandibular joint (TMJ). Experiments were carried out on male Sprague-Dawley rats weighing...
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