- Defective Mitochondrial Function and Motility Due to Mitofusin 1 Overexpression in Insulin Secreting Cells
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Park KS, Wiederkehr A, Wollheim C
- KMID: 2285443
- Korean J Physiol Pharmacol.
- 2012 Feb;16(1):71-77.
- doi: 10.4196/kjpp.2012.16.1.71
Mitochondrial dynamics and distribution is critical for their role in bioenergetics and cell survival. We investigated the consequence of altered fission/fusion on mitochondrial function and motility in INS-1E rat clonal... -
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- Oxidative stress and calcium dysregulation by palmitate in type 2 diabetes
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Ly LD, Xu S, Choi SK, Ha CM, Thoudam T, Cha SK, Wiederkehr A, Wollheim C, Lee IK, Park KS
- KMID: 2375021
- Exp Mol Med.
- 2017 Feb;49(2):e291.
- doi: 10.1038/emm.2016.157
Free fatty acids (FFAs) are important substrates for mitochondrial oxidative metabolism and ATP synthesis but also cause serious stress to various tissues, contributing to the development of metabolic diseases. CD36... -
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