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Detection of Serum Free DNA Hypermethylation in Surgically Resected Adenocarcinoma of the Lung

Park SJ, Kim YT, Park JY, Wi HC, Kang CH, Sung SW, Kim JH

PURPOSE : Aberrant DNA methylation patterns have been commonly associated with human cancers. We have investigated the frequency of DNA hypermethylation in promoter regions from adenocarcinomas of the lung and...
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A Xenoreactive Complement Hemolytic Assay in Xenotransplantation

Kim JY, Kim YT, Lee JR, Wi HC, Lee SH, Kim HS, Kang HJ

  • KMID: 2143213
  • Korean J Lab Med.
  • 2004 Dec;24(6):415-420.
BACKGROUND: Xenotrasplantation is a possible alternative for organ shortage in clinical transplantation, but hyperacute xenograft rejection has been a big huddle. Pre-existing natural xenoreactive antibodies and consequent activation of the...
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Effect of Antibody Titer on Xenograft Survival in Pig-To-Dog Heterotopic Cardiac Xenotransplantation: Opening of Xenotransplantation Era

Lee JR, Kim HK, Kim JY, Choi DY, Lee JH, Wi HC, Kang HJ, Kim YT, Kang BC, Kim JS, Lee HM, Kwak JG, Lee DS, Ahn CR

  • KMID: 1916011
  • Korean J Thorac Cardiovasc Surg.
  • 2004 May;37(5):391-400.
BACKGROUND: Xenotransplantation in discordant species results in immediate and irreversible hyperacute rejection due to natural antibodies, IgM. With this, antibody depletion is one option to reduce hyperacute rejection, we investigated...
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