- Resveratrol augments ER stress and the cytotoxic effects of glycolytic inhibition in neuroblastoma by downregulating Akt in a mechanism independent of SIRT1
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Graham RM, Hernandez , Puerta N, De Angulo , Webster KA, Vanni S
- KMID: 2361497
- Exp Mol Med.
- 2016 Feb;48(2):e210.
- doi: 10.1038/emm.2015.116
Cancer cells typically display increased rates of aerobic glycolysis that are correlated with tumor aggressiveness and a poor prognosis. Targeting the glycolytic pathway has emerged as an attractive therapeutic route... -
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