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Apixaban versus Warfarin in Patients with Chronic Kidney Disease; A Systematic Review and Meta-analysis

Nam JH, Kim CY, Lee YK, Jung DW, Gwak HY, Chung JE

Background: Patients with chronic kidney disease (CKD) are at a high risk of stroke-related morbidity, mortality, and bleeding. However, the overall risk/benefit of anticoagulant therapy among patients with CKD remains...
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Factors predicting poor anticoagulant control on warfarin in a Thai population with non‑valvular atrial fibrillation (NVAF): the ACAChE score

Lertsanguansinchai P, Huntrakul A, Rungpradubvong V, Chokesuwattanaskul  R, Prechawat S

Background: In many low- to middle-income countries in Asia, patients with NVAF usually received warfarin for thromboembolic prevention due to cost-effectiveness. The SAMe-TT2R2 score has been proposed to predict TTR...
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Clinical outcomes among hemodialysis patients with atrial fibrillation: a Korean nationwide population-based study

Kang Y, Choi HY, Kwon YE, Shin JH, Won EM, Yang KH, Oh HJ, Ryu DR

Background: The number of patients requiring dialysis is increasing worldwide, and the atrial fibrillation and atrial flutter (AF) prevalence among hemodialysis (HD) patients is higher than in the general population....
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Severe Airway Obstruction due to Massive Retropharyngeal Hematoma in a Warfarin-Taking Patient with a Normal International Normalized Ratio

Cho HY, Kim HI

Warfarin is used as part of the treatment of various diseases, and laboratory monitoring of its effects is required. Airway hematoma secondary to warfarin is rare, but can be fatal...
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Effect of warfarin discontinuation on the incidence of postoperative bleeding in tooth extraction

Lee JS, Kim MK, Kang SH

Objectives: The number of patients undergoing oral anticoagulant therapy for cardiovascular and cerebrovascular disease is increasing. However, the risk of bleeding after tooth extraction in patients receiving warfarin is unclear....
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Development and Validation of a Novel Warfarin Dosing Algorithm for Korean Patients With VKORC1 1173C

Cho EH, Lee K, Yang M, Choi R, Baek SY, Sohn I, Kim JS, On YK, Bang OY, Cho HJ, Lee SY

BACKGROUND: Differences in the performance of suggested warfarin dosing algorithms among different ethnicities and genotypes have been reported; this necessitates the development of an algorithm with enhanced performance for specific...
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A Large Defect on Nasal Dorsum Treated by Secondary Intention Healing

Kim JY, Park JH

  • KMID: 2502300
  • Korean J Dermatol.
  • 2020 Feb;58(2):122-125.
A 79-year-old man taking warfarin presented with a large defect measuring 3.2×3.4 cm on his nasal dorsum after wide excision of recurrent basal cell carcinoma. A delayed repair was planned;...
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Impact of Anticoagulation Intensity in Korean Patients with Atrial Fibrillation: Is It Different from Western Population?

Lee KH, Cho JG, Lee N, Cho KH, Jeong HK, Park H, Kim Y, Cho JY, Kim MC, Sim DS, Yoon HJ, Yoon N, Kim KH, Hong YJ, Park HW, Ahn Y, Jeong MH, Park JC

BACKGROUND AND OBJECTIVES: Although anticoagulation with warfarin is recommended as an international normalized ratio (INR) of prothrombin time between 2.0 and 3.0 and mean time in the therapeutic range (TTR)...
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Development of Warfarin Talk: A Messenger Chatbot for Patients Taking Warfarin

Lee HS, Kim YR, Shin EJ, Jang HW, Jo YH, Cho YS, Kim JH, Lee JY

Background: Despite the increased use of direct-acting oral anticoagulants, warfarin is still recommended as first-line therapy in patients with mechanical valves or moderate to severe mitral stenosis. Anticoagulation management services...
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A child with Kawasaki disease and genetic warfarin sensitivity from CYP2C9 and VKORC1 gene variants

Lee M, Eun LY

Kawasaki disease (KD) is a common febrile disease in East Asia. Because KD with coronary artery aneurysm (CAA) may predispose to thrombosis, children with KD-associated CAA may need anticoagulation in...
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Randomized Comparison of Thrombus Resolution Outcome between Direct Xa Inhibitor Anticoagulant and Warfarin In Acute Deep Vein Thrombosis

Lee JH, Park KH

Purpose: Newly developed factor Xa inhibitor anticoagulants (Xaban) produced non-inferior outcomes in terms of venous thromboembolism (VTE) recurrence and safety. On the other hand, thrombus resolution (TR), a factor associated...
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Comparison of the Efficacy and Safety of Warfarin and Antiplatelet Therapy in Patients with Atrial Fibrillation and End-Stage Renal Disease

Han D, Uhm JS, Park JT, Kim TH, Joung B, Yoo TH, Pak HN, Kang SW, Lee MH

BACKGROUND/AIMS: The optimal strategy for anticoagulation treatment in patients with atrial fibrillation (AF) and end-stage renal disease (ESRD) has not been established. We evaluated the efficacy and bleeding risk of...
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Cost-Effectiveness of Rivaroxaban Compared to Warfarin for Stroke Prevention in Atrial Fibrillation

Kim H, Kim H, Cho SK, Kim JB, Joung B, Kim C

BACKGROUND AND OBJECTIVES: Rivaroxaban is noninferior to warfarin for preventing stroke or systemic embolism in patients with high-risk atrial fibrillation (AF) and is associated with a lower rate of intracranial...
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Real World Comparison of Rivaroxaban and Warfarin in Korean Patients with Atrial Fibrillation: Propensity Matching Cohort Analysis

Jeong HK, Lee KH, Park HW, Yoon NS, Kim MC, Lee N, Kim JS, Ahn Y, Jeong MH, Park JC, Cho JG

Rivaroxaban has emerged as a potential alternative to warfarin for the prevention of thromboembolism in patients with atrial fibrillation (AF). However, there has been concern for the risk of major...
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Renal Cholesterol Embolism during Warfarin Treatment

Yoon S, Bae JS, Lee JH, Song HK, Yoo J, Kang DG, Seo JY, Nam ES, Shin DH, Kim Y

Cholesterol embolization syndrome (CES) usually occurs after endovascular procedures, it may also occurs after using anticoagulants and thrombolytics. We report a case of 66-year-old man with sudden elevation of creatinine...
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Adaptation of New Oral Anticoagulants for Warfarin Anticoagulated Patient with Traumatic Ongoing Hemorrhage

Ye JB, Sul YH, Lee JY, Go SJ, Choi JH

The traditional drug for anticoagulation in those with a high risk of thrombosis is a vitamin K antagonist, such as warfarin. On the other hand, this drug has several limitations...
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Anticoagulation for Stroke Prevention in Older Adults with Atrial Fibrillation and Comorbidity: Current Evidence and Treatment Challenges

Sabbag A, Yao X, Siontis KC, Noseworthy PA

The burden of atrial fibrillation (AF) is projected to increase substantially over the next decade in parallel with the aging of the population. The increasing age, level of comorbidity, and...
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Quality of Anticoagulation with Warfarin in Korean Patients with Atrial Fibrillation and Prior Stroke: A Multicenter Retrospective Observational Study

Hong KS, Kim YK, Bae HJ, Nam HS, Kwon SU, Bang OY, Cha JK, Yoon BW, Rha JH, Lee BC, Park JM, Park MS, Lee J, Choi JC, Kim DE, Lee KB, Park TH, Lee JS, Kim SE, Lee J

BACKGROUND AND PURPOSE: The quality of anticoagulation is critical for ensuring the benefit of warfarin, but this has been less well studied in Korean ischemic stroke patients with atrial fibrillation...
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Spontaneous elbow hemarthrosis identified by point-of-care ultrasound

Mackenzie , McCorvey S

Traumatic or spontaneous hemarthroses are an important cause of joint effusions, and can complicate innate or acquired coagulopathies. The elbow is an unusual location for a spontaneous hemarthrosis; we describe...
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Hypersensitivity to ticagrelor and low response to clopidogrel: a case report

Dai J, Lyu S, Ge C

Ticagrelor is widely used to treat acute coronary syndrome. Hypersensitivity reaction of ticagrelor is rarely recognized. A low response to clopidogrel, which occurs in up to 23% of patients, is...
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