- Engineering a High-Affinity PD-1 Peptide for Optimized Immune Cell-Mediated Tumor Therapy
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Chen Y, Huang H, Liu Y, Wang Z, Wang L, Wang Q, Zhang Y, Wang H
- KMID: 2528206
- Cancer Res Treat.
- 2022 Apr;54(2):362-374.
- doi: 10.4143/crt.2021.424
Purpose The purpose of this study was to optimize a peptide (nABP284) that binds to programmed cell death protein 1 (PD-1) by a computer-based protocol in order to increase its affinity.... -
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- Dissecting Causal Relationships Between Gut Microbiota, Blood Metabolites, and Stroke: A Mendelian Randomization Study
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Wang Q, Dai H, Hou T, Hou Y, Wang T, Lin H, Zhao Z, Li M, Zheng R, Wang S, Lu J, Xu Y, Liu R, Ning G, Wang W, Bi Y, Zheng J, Xu M
- KMID: 2546436
- J Stroke.
- 2023 Sep;25(3):350-360.
- doi: 10.5853/jos.2023.00381
Background and Purpose We investigated the causal relationships between the gut microbiota (GM), stroke, and potential metabolite mediators using Mendelian randomization (MR). Methods We leveraged the summary statistics of GM (n=18,340... -
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- Quantitative Measurement of Serum MicroRNA-21 Expression in Relation to Breast Cancer Metastasis in Chinese Females
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Wang G, Wang L, Sun S, Wu J, Wang Q
- KMID: 2363183
- Ann Lab Med.
- 2015 Mar;35(2):226-232.
- doi: 10.3343/alm.2015.35.2.226
BACKGROUND: Breast cancer is the most common type of cancer in females. Aberrant expression of microRNA-21 (miR-21) has previously been reported in breast cancer tissue. The aim of this study... -
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- Comparative Efficacy of Ivermectin and Levamisole for Reduction of Migrating and Encapsulated Larvae of Baylisascaris transfuga in Mice
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Fu Y, Nie HM, Niu LL, Xie Y, Deng JB, Wang Q, Yang GY, Gu XB, Wang SX
- KMID: 1090614
- Korean J Parasitol.
- 2011 Jun;49(2):145-151.
- doi: 10.3347/kjp.2011.49.2.145
The comparative efficacy of 2 anthelmintics (ivermectin and levamisole) against Baylisascaris transfuga migrating and encapsulated larvae was studied in mice. A total of 60 BALB/c mice inoculated each with about... -
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- Risk factors affecting postoperative pulmonary function in congenital diaphragmatic hernia
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Wang Q, Liu Q, Zang J, Wang J, Chen J
- KMID: 2500821
- Ann Surg Treat Res.
- 2020 Apr;98(4):206-213.
- doi: 10.4174/astr.2020.98.4.206
Purpose: It is well known that congenital diaphragmatic hernia (CDH) in infants impacts pulmonary function rehabilitation after surgery. However, the risk factors of postoperative pulmonary function are still unclear. In... -
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- Psoriatic Serum Induce an Abnormal Inflammatory Phenotype and a Decreased Immunosuppressive Function of Mesenchymal Stem Cells
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Wang F, Hou R, Li J, Zhao X, Wang Q, Zhang K, Li X
- KMID: 2529787
- Int J Stem Cells.
- 2022 May;15(2):155-163.
- doi: 10.15283/ijsc20210
Background and Objectives: Mesenchymal stem cells (MSCs) have immunomodulatory function and participate in the pathogenesis of many immunoregulation-related diseases, including psoriasis. Previously, we found that MSCs from psoriatic lesions overexpress... -
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- Intracellular trafficking of TREM2 is regulated by presenilin 1
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Zhao Y, Li X, Huang T, Jiang LL, Tan Z, Zhang M, Cheng IH, Wang X, Bu G, Zhang YW, Wang Q, Xu H
- KMID: 2402942
- Exp Mol Med.
- 2017 Dec;49(12):e405.
- doi: 10.1038/emm.2017.200
Genetic mutations in triggering receptor expressed on myeloid cells 2 (TREM2) have been linked to a variety of neurodegenerative diseases including Alzheimer’s disease, amyotrophic lateral sclerosis, frontotemporal dementia and Parkinson’s... -
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- Fertility-preserving treatment outcome in endometrial cancer or atypical hyperplasia patients with polycystic ovary syndrome
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Wang L, Luo X, Wang Q, Lv Q, Wu P, Liu W, Chen X
- KMID: 2526146
- J Gynecol Oncol.
- 2021 Sep;32(5):e70.
- doi: 10.3802/jgo.2021.32.e70
Objective This study aimed to investigate the impact of polycystic ovary syndrome (PCOS) on fertility-sparing treatment in young patients with atypical endometrial hyperplasia (AEH) or endometrioid endometrial cancer (EEC). Methods A total of... -
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- SKF96365 impedes spinal glutamatergic transmission-mediated neuropathic allodynia
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Wang Q, Zhang Y, Du Q, Zhao X, Wang W, Zhai Q, Xiang M
- KMID: 2537502
- Korean J Physiol Pharmacol.
- 2023 Jan;27(1):39-48.
- doi: 10.4196/kjpp.2023.27.1.39
Spinal nerve injury causes mechanical allodynia and structural imbalance of neurotransmission, which were typically associated with calcium overload. Storeoperated calcium entry (SOCE) is considered crucial elements-mediating intracellular calcium homeostasis, ion... -
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- Application of HTB-SiHa Cells Transfected with a Recombinant Plasmid for External Quality Assessment of Chlamydia trachomatis PCR
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Zhang K, Huo H, Sun Y, Wang L, Zhang R, Lin G, Xie J, Wang Q, Li J
- KMID: 1791950
- Ann Lab Med.
- 2014 Sep;34(5):360-366.
- doi: 10.3343/alm.2014.34.5.360
BACKGROUND: The participation of laboratories in external quality assessment (EQA) programs is required for the quality assurance of nucleic acid amplification of Chlamydia trachomatis. This study aimed to construct a... -
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- Prevalence of Seasonal Influenza Viruses and Pandemic H1N1 Virus in Beijing from 2008 to 2012
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Cui S, Tian L, Peng X, Lu G, Shi W, Meng D, Wang Q
- KMID: 2434492
- Ann Lab Med.
- 2012 Nov;32(6):455-456.
No abstract available. -
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- Feasibility of Three-Dimensional Balanced Steady-State Free Precession Cine Magnetic Resonance Imaging Combined with an Image Denoising Technique to Evaluate Cardiac Function in Children with Repaired Tetralogy of Fallot
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Peng Y, Su X, Hu L, Wang Q, Ouyang R, Sun A, Guo C, Yao X, Zhang Y, Wang L, Zhong Y
- KMID: 2519438
- Korean J Radiol.
- 2021 Sep;22(9):1525-1536.
- doi: 10.3348/kjr.2020.0850
Objective: To investigate the feasibility of cine three-dimensional (3D) balanced steady-state free precession (b-SSFP) imaging combined with a non-local means (NLM) algorithm for image denoising in evaluating cardiac function in... -
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- Serological and molecular epidemiology of Japanese encephalitis virus infections in swine herds in China, 2006–2012
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Chai C, Wang Q, Cao S, Zhao Q, Wen Y, Huang X, Wen X, Yan Q, Ma X, Wu R
- KMID: 2402706
- J Vet Sci.
- 2018 Jan;19(1):151-155.
- doi: 10.4142/jvs.2018.19.1.151
Japanese encephalitis virus (JEV) is a mosquito-borne, zoonotic flavivirus causing viral encephalitis in humans and reproductive disorder in swine. JEV is prevalent throughout China in human; however, spatiotemporal analysis of... -
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- A two-component signal transduction system contributes to the virulence of Riemerella anatipestifer
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Wang Q, Chen M, Zhang W
- KMID: 2407625
- J Vet Sci.
- 2018 Mar;19(2):260-270.
- doi: 10.4142/jvs.2018.19.2.260
Similar to other studies of bacterial pathogens, current studies of the pathogenesis of Riemerella anatipestifer (RA) are focused mainly on in vitro culture conditions. To elucidate further the pathogenesis of... -
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- Intra-Articular Injection of miR-29a-3p of BMSCs Promotes Cartilage Self-Repairing and Alleviates Pain in the Rat Osteoarthritis
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Wang Q, Chen Y, Shen X, Chen J, Li Y
- KMID: 2522578
- Tissue Eng Regen Med.
- 2021 Dec;18(6):1045-1055.
- doi: 10.1007/s13770-021-00384-7
BACKGROUND: Stem cells intra-articular injection stagey indicated a potential therapeutic effect on improving the pathological progress of osteoarthritis (OA). However, the long-term effect of stem cells intra-articular injection on the... -
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- Epidemiological investigation and phylogenetic analysis of Classical Swine Fever virus in Yunnan province from 2015 to 2021
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Yao J, Su L, Wang Q, Gao L, Xie J, He Y, Shu X, Song C, Chai J, Zhang Y, Yang S
- KMID: 2532286
- J Vet Sci.
- 2022 Jul;23(4):e57.
- doi: 10.4142/jvs.22042
Background: Classical swine fever virus (CSFV), the causative agent of classical swine fever (CFS), is a highly contagious disease that poses a serious threat to Chinese pig populations. Objectives: Many provinces... -
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- The Associations of Family Functioning, General Well-Being,and Exercise with Mental Health among End-Stage RenalDisease Patients
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Wang Q, Liu H, Ren Z, Xiong W, He M, Li N, Fan X, Guo X, Li X, Shi H, Zha S, Zhang X
- KMID: 2500242
- Psychiatry Investig.
- 2020 Apr;17(4):356-365.
- doi: 10.30773/pi.2019.0204
Objective This study aims to explore the relationships of family functioning, general well-being, and exercise with psychological distress. Furthermore, we investigated the special roles of general well-being and exercise on the... -
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- Short-Chain Fatty Acids Attenuate Renal Fibrosis and Enhance Autophagy of Renal Tubular Cells in Diabetic Mice Through the HDAC2/ULK1 Axis
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Ma X, Wang Q
- KMID: 2531387
- Endocrinol Metab.
- 2022 Jun;37(3):432-443.
- doi: 10.3803/EnM.2021.1336
Background: This study investigated the effect of short-chain fatty acids (SCFAs) on diabetes in a mouse model. Methods: Autophagy in Akita mice and streptozocin (STZ)-induced diabetic C57BL/6 mice was determined by... -
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- Prevalence of Cystic Echinococcosis in Slaughtered Sheep as an Indicator to Assess Control Progress in Emin County, Xinjiang, China
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Yang S, Wu W, Tian T, Zhao J, Chen K, Wang Q, Feng Z
- KMID: 2381842
- Korean J Parasitol.
- 2015 Jun;53(3):355-359.
- doi: 10.3347/kjp.2015.53.3.355
Hydatid disease imposing serious threat on human health and great loss in livenotstock pastoralism remains a major public health problem in western China. To assess and monitor the effect of... -
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- Expression of FMD virus-like particles in yeast Hansenula polymorpha and immunogenicity of combine with CpG and aluminum adjuvant
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Zhang J, Ge J, Li J, Li J, Zhang Y, Shi Y, Sun J, Wang Q, Zhang X, Zhao X
- KMID: 2539432
- J Vet Sci.
- 2023 Jan;24(1):e15.
- doi: 10.4142/jvs.22227
Background: Inactivated vaccines are limited in preventing foot-and-mouth disease (FMD) due to safety problems. Recombinant virus-like particles (VLPs) are an excellent candidate for a novel vaccine for preventing FMD, given... -
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