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The Catechol-O-Methyltransferase Val158Met Polymorphism Contributes to the Risk of Breast Cancer in the Chinese Population: An Updated Meta-Analysis

Wan GX, Cao YW, Li WQ, Li YC, Li F

  • KMID: 2353070
  • J Breast Cancer.
  • 2014 Jun;17(2):149-156.
PURPOSE: Catechol-O-methyltransferase (COMT) enzyme plays a central role in estrogen-induced carcinogenesis. Emerging evidence from association studies has revealed that the functional Val158Met polymorphism (rs4680 G>A) of the Catechol-O-methyltransferase gene (COMT)...
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