- p38 Mitogen-Activated Protein Kinase Is Involved in Interleukin-6 Secretion from Human Ligamentum Flavum–Derived Cells Stimulated by Tumor Necrosis Factor-α
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Yagi K, Goto Y, Kato K, Suzuki N, Kondo A, Waseda Y, Mizutani J, Kawaguchi Y, Joyo Y, Waguri-Nagaya Y, Murakami H
- KMID: 2523370
- Asian Spine J.
- 2021 Dec;15(6):713-720.
- doi: 10.31616/asj.2020.0425
Study Design: Human ligamentum flavum–derived cells (HFCs) were obtained from surgical samples for a basic experimental study. Purpose: We sought to evaluate the inflammatory response of human ligamentum flavum cells to... -
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- Transforming Growth Factor-β Induces Interleukin-6 Secretion from Human Ligamentum Flavum–Derived Cells through Partial Activation of p38 and p44/42 Mitogen-Activated Protein Kinases
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Goto Y, Kato K, Yagi K, Kawaguchi Y, Yonezu H, Koshimae T, Waguri-Nagaya Y, Murakami H, Suzuki N
- KMID: 2549412
- Asian Spine J.
- 2023 Dec;17(6):997-1003.
- doi: 10.31616/asj.2023.0025
Study Design: This experimental study was performed using human ligamentum flavum–derived cells (HFCs). Purpose: To investigate the intracellular signaling mechanism of interleukin-6 (IL-6) secretion in transforming growth factor-β (TGF- β)-stimulated HFCs. Overview... -
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