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Comparison of three caval reconstruction techniques in orthotopic liver transplantation: result from a university hospital from Bangkok, Thailand

Uthaithammarat T, Sutherasan M, Nonthasoot B, Taesombat W, Vorasittha A, Nivatvongs S, Sirichindakul B

Background: In orthotopic liver transplantation, three caval reconstruction techniques are commonly being performed worldwide. These are conventional, piggyback technique and side-to-side cavocaval anastomosis (STSCCA). Each has its own advantages and...
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Effects of cytochrome P450 3A5 (CYP3A5) on pharmacokinetic profiles of tacrolimus in Thai patients with liver transplantation

Vorasittha A, Chariyavilaskul P, Tanathitiphuwarat N, Noonthasoot B

Background: Tacrolimus, an immunosuppressant used in liver transplant patients, has narrow therapeutic index and large inter-individual pharmacokinetic variability, partly due to the pharmacogenetic variation in the main drug-metabolizing enzyme cytochrome...
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