- Phospholipase D2 promotes degradation of hypoxia-inducible factor-1alpha independent of lipase activity
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Park MH, Bae SS, Choi KY, Min DS
- KMID: 2359883
- Exp Mol Med.
- 2015 Nov;47(11):e196.
- doi: 10.1038/emm.2015.87
Hypoxia-inducible factor-1alpha (HIF-1alpha) is a key transcriptional mediator that coordinates the expression of various genes involved in tumorigenesis in response to changes in oxygen tension. The stability of HIF-1alpha protein... -
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