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1 Nur77 upregulates HIF-alpha by inhibiting pVHL-mediated degradation

Kim BY, Kim H, Cho EJ, Youn HD

KMID: 1103590
Exp Mol Med.
2008 Feb;40(1):71-83.
doi: 10.3858/emm.2008.40.1.71

In this study, we investigated the role of Nur77, an orphan nuclear receptor, in HIF-alpha transcriptional activity. We found that Nur77 associates and stabilizes HIF-1alpha via indirect interaction. Nur77 was...

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