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Consecutive Reversible Changes of Peripheral Nerve Conduction in Tetrodotoxification

Park JH, Kim SM, Bae JC, Kwon KH, Lee BC, Na H

  • KMID: 2188787
  • J Korean Geriatr Soc.
  • 1999 Sep;3(2):102-107.
Tetrodotoxin (TTX) cause neurologic dysfunction by blocking the voltage-gated sodium channels located in all of the peripheral nerves and muscles. We experienced two patients presenting with generalized motor weakness after...
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Polymorphisms in the Voltage-gated Sodium Channel Genes and Antiepileptic Efficacy of Carbamazepine

Jang SY, Kim MK, Nam TS, Kim JT, Choi SM, Lee SH, Park MS, Kim BC, Cho KH

  • KMID: 2185031
  • J Korean Neurol Assoc.
  • 2009 May;27(2):147-153.
BACKGROUND: Voltage-gated sodium channels are responsible for the initial-depolarization component of action potentials in brain neurons, and hence they are the target for widely used antiepileptic drugs such as carbamazepine...
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Colonic Hypersensitivity and Sensitization of Voltage-gated Sodium Channels in Primary Sensory Neurons in Rats with Diabetes

Hu J, Song ZY, Zhang HH, Qin X, Hu S, Jiang X, Xu GY

  • KMID: 2379712
  • J Neurogastroenterol Motil.
  • 2016 Jan;22(1):129-140.
  • doi: 10.5056/jnm15091
BACKGROUND/AIMS: Patients with long-standing diabetes often demonstrate intestinal dysfunction and abdominal pain. However, the pathophysiology of abdominal pain in diabetic patients remains elusive. The purpose of study was to determine...
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Preemptive application of QX-314 attenuates trigeminal neuropathic mechanical allodynia in rats

Yoon JH, Son JY, Kim MJ, Kang SH, Ju JS, Bae YC, Ahn DK

The aim of the present study was to examine the effects of preemptive analgesia on the development of trigeminal neuropathic pain. For this purpose, mechanical allodynia was evaluated in male...
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Glial Cell Line-derived Neurotrophic Factor-overexpressing Human Neural Stem/Progenitor Cells Enhance Therapeutic Efficiency in Rat with Traumatic Spinal Cord Injury

Hwang K, Jung K, Kim IS, Kim M, Han J, Lim J, Shin JE, Jang JH, Park KI

Spinal cord injury (SCI) causes axonal damage and demyelination, neural cell death, and comprehensive tissue loss, resulting in devastating neurological dysfunction. Neural stem/progenitor cell (NSPCs) transplantation provides therapeutic benefits for...
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