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Molecular characterization and phylogenetic analysis of pseudorabies virus variants isolated from Guangdong province of southern China during 2013–2014

Fan J, Zeng X, Zhang G, Wu Q, Niu J, Sun B, Xie Q, Ma J

Outbreaks of pseudorabies (PR) have occurred in southern China since late 2011, resulting in significant economic impacts on the swine industry. To identify the cause of PR outbreaks, especially among...
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Expression of the plant viral protease NIa in the brain of a mouse model of Alzheimer's disease mitigates Abeta pathology and improves cognitive function

Kim TK, Han HE, Kim H, Lee JE, Choi D, Park WJ, Han PL

  • KMID: 1402318
  • Exp Mol Med.
  • 2012 Dec;44(12):740-748.
The plant viral protease, NIa, has a strict substrate specificity for the consensus sequence of Val-Xaa-His-Gln, with a scissoring property after Gln. We recently reported that NIa efficiently cleaved the...
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Genomic diversity of the Avian leukosis virus subgroup J gp85 gene in different organs of an infected chicken

Meng F, Li X, Fang J, Gao Y, Zhu L, Xing G, Tian F, Gao Y, Dong X, Chang S, Zhao P, Cui Z, Liu Z

The genomic diversity of Avian leukosis virus subgroup J (ALV-J) was investigated in an experimentally infected chicken. ALV-J variants in tissues from four different organs of the same bird were...
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Imaging of Viral Thymidine Kinase Gene Expression by Replicating Oncolytic Adenovirus and Prediction of Therapeutic Efficacy

Kim EJ, Yoo JY, Choi YH, Ahn KJ, Lee JD, Yun CO, Yun M

PURPOSE: We have used a genetically attenuated adenoviral vector which expresses HSVtk to assess the possible additive role of suicidal gene therapy for enhanced oncolytic effect of the virus. Expression...
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