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Chemotherapy-induced Drug Reaction due to Extravasation of Vinorelbine

Jang MS, Kim JH, Yang MH, Lee KH, Han SH, Suh KS

  • KMID: 2382993
  • Korean J Dermatol.
  • 2016 Jun;54(5):372-376.
Vinorelbine, a vinca alkaloid anticancer drug, is widely used to treat various cancers. Several dermatological side effects of vinorelbine, such as acral erythema, phlebitis, and severe extravasation reactions, have been...
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A Randomized Phase II Trial of Capecitabine Plus Vinorelbine Followed by Docetaxel Versus Adriamycin Plus Cyclophosphamide Followed by Docetaxel as Neoadjuvant Chemotherapy for Breast Cancer

Yoo C, Kim SB, Ahn JH, Kim JE, Jung KH, Gong GY, Son BH, Ahn SH, Ahn SD, Kim HH, Shin HJ, Kim WK

PURPOSE: Given the promising activity of capecitabine and vinorelbine in metastatic breast cancer, this randomized phase II trial evaluated the efficacy and safety of this combination as neoadjuvant chemotherapy in...
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Comparison of CVF (Cyclophosphamide+Vinorelbine+5-Fluorouracil) and CMF (Cyclophosphamide+Methotrexate+5-Fluorouracil) Adjuvant Chemotherapy in Early Breast Cancer

Gwak G, Park K, Shin E, Han S, Kim JY, Kim H, Kim YD, Kim HJ, Kim KW, Bae BN, Yang KH, Cho H, Park SJ

  • KMID: 2394777
  • J Breast Cancer.
  • 2011 Sep;14(3):223-228.
PURPOSE: Our study aimed to evaluate the feasibility of adjuvant cyclophosphamide/vinorelbine/5-fluorourail (CVF) chemotherapy as an alternative to cyclophosphamide/methotrexate/5-fluorouracil (CMF) chemotherapy for treating early breast cancer. METHODS: One hundred and forty-nine patients...
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Phase II Study of Vinorelbine Plus Trastuzumab in HER2 Overexpressing Metastatic Breast Cancer Pretreated with Anthracyclines and Taxanes

Lee YR, Huh SJ, Lee DH, Yoon HH, Seol YM, Choi YJ, Kwon KA, Lee S, Oh SY, Kim SH, Kim HJ, Kwon HC

PURPOSE: The role of first-line trastuzumab-based therapy has been firmly established in patients with human epidermal growth factor receptor-2 (HER2) positive metastatic breast cancer. In this trial, we evaluated the...
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Phase II Study of Vinorelbine Plus Ifosfamide in Patients with Taxane-resistant Metastatic Breast Cancer

Lee S, Oh SY, Kwon HC, Kim SH, Kwon KA, Hsing CT, Kim DC, Lee JH, Lee HS, Lee MR, Cho SH, Kim HJ

PURPOSE: The patients with metastatic breast cancer are routinely exposed to taxane and anthracycline as neoadjuvant, adjuvant, and palliative chemotherapeutic agents. This study was designed to evaluate the efficacy and...
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Gemcitabine and Vinorelbine Combination Chemotherapy in Anthracycline- and Taxane-pretreated Advanced Breast Cancer

Kim HJ, Kim JS, Seo MD, Oh SY, Oh DY, Kim JH, Lee SH, Kim DW, Im SA, Kim TY, Heo DS, Bang YJ

  • KMID: 2166006
  • Cancer Res Treat.
  • 2008 Jun;40(2):81-86.
PURPOSE: Anthracycline and taxanes are effective agents in advanced breast cancer and prolong survival times. Some patients achieve prolongation of life with capecitabine, gemcitabine, or vinorelbine, even after failure of...
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Gemcitabine Plus Vinorelbine as Second-line Chemotherapy of the Patients of Previously Treated Non-small Cell lung Cancer: Phase II Trial

Jang PS, Kang HM, Lee JE, Kwon SJ, An JY, Lee YS, Jeong SS, Kim JO, Kim SY

  • KMID: 2318546
  • Tuberc Respir Dis.
  • 2005 Apr;58(4):344-351.
BACKGROUND: Both gemcitabine and vinorelbine are effective anticancer drugs with mild toxicity on non-small cell lung cancer, and monotherapy of these drugs are effective as a second-line chemotherapy. The aim...
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Phase II Study of Gemcitabine and Vinorelbine as a Combination Chemotherapy for the Second-Line Treatment of Nonsmall Cell Lung Carcinoma

Lee E, Ha E, Park S, Hur G, Jung K, Jeong H, Lee S, Kim J, Lee S, Sin C, Shim J, In K, Kang K, Yoo S

  • KMID: 2318694
  • Tuberc Respir Dis.
  • 2005 Nov;59(5):510-516.
BACKGROUND: Lung cancer is the leading cause of cancer deaths in Korea and the number of lung cancer deaths is increasing. The higher response rates, decreased toxicity and improved...
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Capecitabine and Vinorelbine in Patients with Metastatic Breast Cancer Previously Treated with Anthracycline and Taxane

Ahn JH, Kim SB, Kim TW, Ahn SH, Kim SM, Park JM, Lee JS, Kang YK, Kim WK

We have evaluated the efficacy and safety of the combination of capecitabine and vinorelbine in metastatic breast cancer (MBC) patients previously treated with anthracycline-and taxane-containing regimens. Between April 2000 and...
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Phase II Study of Gemcitabine and Vinorelbine as Second-Line Chemotherapy in Non-Small Cell Lung Cancer

Kim YJ, Sohn JH, Kim C, Kim YT, Kim HJ, Ahn JB, Kim SK, Chang J, Yoo NC, Kim JH, Cho JY

  • KMID: 1972896
  • Cancer Res Treat.
  • 2003 Aug;35(4):294-298.
PURPOSE: With the increased use of chemotherapy for non small cell lung cancer (NSCLC), a growing group of patients can now be considered for second-line chemotherapy. However, guidelines for the...
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Vinorelbine Monotherapy on Advanced Non-small Cell Lung Cancer

Kim MH, Park HS, An JY, Kwon SJ, Lee YS, Jeong SS, Kim JO, Kim SY

  • KMID: 2318379
  • Tuberc Respir Dis.
  • 2002 May;52(5):475-484.
BACKGROUND: Unresectable non-small cell lung cancer has a poor response to chemotherapy and has an unfortunate prognosis. More effective and less toxic cytotoxic agents are needed to improve the outcome...
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Effect of Vinorelbine, Ifosfamide and Cisplatin Combination Chemotherapy in Stage III-IV Non-Small-Cell Lung Cancer

Kim YC, Lee SY, Cho HJ, Kim JA, Song SH, Kim CH, Kim HK, Ahn MI, You JY, Kim SW, Cho DG, Cho KD, Kang JH

  • KMID: 1972940
  • Cancer Res Treat.
  • 2002 Oct;34(5):352-356.
PURPOSE: To evaluate the response rates, toxicitiesy, and survival rates, to vinorelbine (Navelbine(R)), cisplatin and ifosfamide combination chemotherapy, of the patients with inoperable NSCLC (stage III and IV), who received...
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A phase II trial of navelbine, ifosfamide, and cisplatin (NIP) in patients with previously untreated advanced non-small cell lung cancer (NSCLC)

Kim TW, Kim SH, Choi SJ, Choi JS, Kim SW, Choi EK, Suh C, Lee JS, Kim WS, Kim DS, Kim WD, Kim WK

  • KMID: 2306148
  • Korean J Med.
  • 2001 May;60(5):472-478.
BACKGROUND: We performed a phase II study to determine the activity and toxicity of Navelbine, Ifosfamide, and Cisplatin (NIP) combination in patients with stage IIIB-IV non-small cell lung cancer (NSCLC)....
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Combination Chemotherapy with Vinorelbine and Ifosfamide in Patients with Advanced Non-Small Cell Lung Cancer

Kim SG, Kim SH, Kwon HC, Lee KH, Kim JS, Kim HJ

  • KMID: 2174991
  • J Korean Cancer Assoc.
  • 2001 Apr;33(2):163-167.
PURPOSE: We conducted a phase II study of vinorelbine and ifosfamide combination chemotherapy in patients with advanced or recurrent non-small cell lung cancer (NSCLC) to evaluate response rate, response duration,...
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Combination Chemotherapy with Mitomycin C, Vinorelbine, and Cisplatin (MVrP) in Patients with Advanced Non-Small Cell Lung Cancer

Kim HG, Lee GW, Lee DH, Hwang IG, Shim KS, Lee WS, Lee JD, Jang JS, Hwang YS, Lee JS

  • KMID: 1804427
  • Cancer Res Treat.
  • 2001 Oct;33(5):377-384.
PURPOSE: A phase II study was conducted in patients with advanced non-small cell lung cancer (NSCLC) in order to evaluate the efficacy and toxicity of the combination chemotherapy regimen of...
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Phase II Trial of Vinorelbine and Cisplatin Chemotherapy in Advanced Non-Small Cell Lung Cancer

Joh YH, Kim TY, Na II, Oh DY, Kim BS, Kim JH, Kim DY, Lee SH, Yoo CG, Lee CT, Kim YW, Heo DS, Bang YJ, Han SK, Shim YS, Kim NK

  • KMID: 1804426
  • Cancer Res Treat.
  • 2001 Oct;33(5):373-376.
PURPOSE: Platinum-based chemotherapy has conferred a modest but significant survival benefit and the introduction of newer drugs has led to achieve higher response rate in patients with advanced non-small cell...
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Combination chemotherapy with vinorelbine and ifosfamide for advanced non-small cell lung cancer

Cho EK, Hong SH, Bang SM, Lee HK, Park JW, Jeong SH, Nam G, Shin DB, Lee JH

  • KMID: 1600623
  • Korean J Med.
  • 2001 Jan;60(1):70-76.
BACKGROUND: Although cisplatin (CDDP)-based chemotherapy is currently considered to be the most active treatment for advanced non-small cell lung cancer (NSCLC), ultimate prognosis still remains poor. More effective cytotoxic agents...
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Venous Irritation Incidence Associated with Vinorelbine Tartrate Injection Time

Hur KW, Jung JE, Seo JH, Choi CW, Kim BS, Shin SW, Kim YH, Kim JS

  • KMID: 2007086
  • J Korean Cancer Assoc.
  • 2000 Aug;32(4):699-704.
PURPOSE: This study was to determine the incidence and severity of venous irriation in patients receiving vinorelbine tartrate (Navelbine ) in combination chemotherapy. MATERIAL AND METHODS: Twenty four patients histologically confirmed...
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A Phase II Study with Vinorelbine and Carboplatin in Patients with Advanced Non-small Cell Lung Cancer

Kim JL, Kim BS, Na BJ, So MJ, Lee JH, Chung OY, Lee GL, Roh YH

  • KMID: 2007085
  • J Korean Cancer Assoc.
  • 2000 Aug;32(4):690-698.
PURPOSE: To evaluate the efficacy and safety of vinorelbine and carboplatin in advanced non- small-cell lung cancer (NSCLC). MATERIALS AND METHODS: Between August 1998 and July 1999, 25 patients were enrolled....
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Efficacy of Combination Chemotherapy with Vinorelbine, Ifosfamide, and Cisplatin in Patients with Advanced Non-Small Cell Lung Cancer

Chang HM, Lee JA, Ahn JS, Woo IS, Park YI, Son JW, Lee SJ, Kim DK, Mo EK, Park MJ, Lee MG, Hyun IG, Jung KS, Park YS

  • KMID: 2175027
  • J Korean Cancer Assoc.
  • 2000 Jun;32(3):612-618.
PURPOSE: To evaluate the efficacy and toxicity of combination chemotherapy with vinorelbine, ifosfamide, and cisplatin in patients with advanced non-small cell lung cancer. MATERIALS AND METHODS: Patients with unresectable, pathologically proven non-small...
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