- Evaluation of a tyrosine kinase peptide microarray for tyrosine kinase inhibitor therapy selection in cancer
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Labots M, Gotink KJ, Dekker H, Azijli K, van der Mijn JC, Huijts CM, Piersma SR, Jiménez C, Verheul HM
- KMID: 2367555
- Exp Mol Med.
- 2016 Dec;48(12):e279.
- doi: 10.1038/emm.2016.114
Personalized cancer medicine aims to accurately predict the response of individual patients to targeted therapies, including tyrosine kinase inhibitors (TKIs). Clinical implementation of this concept requires a robust selection tool.... -
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- Evaluation of several methodological challenges in circulating miRNA qPCR studies in patients with head and neck cancer
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Poel D, Buffart TE, Oosterling-Jansen J, Verheul HM, Voortman J
- KMID: 2440049
- Exp Mol Med.
- 2018 Mar;50(3):e454.
- doi: 10.1038/emm.2017.288
Circulating microRNAs (ci-miRNAs) in blood have emerged as promising diagnostic, prognostic and predictive biomarkers in cancer. Many clinical studies currently incorporate studies that assess ci-miRNAs. Validation of the clinical significance... -
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