- Detection of an Ala601Thr Mutation of Plasminogen Gene in 3 out of 36 Korean Patients with Deep Vein Thrombosis
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Song KS, Lee SM, Choi JR
- KMID: 2157617
- J Korean Med Sci.
- 2003 Apr;18(2):167-170.
- doi: 10.3346/jkms.2003.18.2.167
Plasminogen is a key proenzyme in the fibrinolytic and thrombolytic systems. Congenital deficiency of plasminogen and molecular abnormality of plasminogen (dysplasminogenemia) have been reported in association with the thrombotic tendency... -
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- Low prevalence of activated protein C resistance and coagulation factor V Arg506 to Gln mutation among Korean patients with deep vein thrombosis
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Kim TW, Kim WK, Lee JH, Kim SB, Kim SW, Suh C, Lee KH, Lee JS, Seo EJ, Chi HS, Kim SH
- KMID: 1038437
- J Korean Med Sci.
- 1998 Dec;13(6):587-590.
- doi: 10.3346/jkms.1998.13.6.587
Activated protein C (APC) is a naturally occurring anticoagulant that interacts with factor V and VIII to inhibit the clotting cascade. The prevalence of APC resistance among Korean patients... -
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- A molecular model of a point mutation (Val297Met) in the serine protease domain of protein C
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Song KS, Park YS, Choi JR, Kim HK, Park Q
- KMID: 755027
- Exp Mol Med.
- 1999 Mar;31(1):47-51.
A heterozygous GTG to ATG (Val297Met) mutation was detected in a patient with inherited protein C deficiency and deep vein thrombosis. Cosegregation of the mutation with protein C deficiency was observed through... -
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