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B-cell translocation gene 2 positively regulates GLP-1-stimulated insulin secretion via induction of PDX-1 in pancreatic beta-cells

Hwang SL, Kwon O, Kim SG, Lee IK, Kim YD

  • KMID: 2154244
  • Exp Mol Med.
  • 2013 May;45(5):e25.
Glucagon-like peptide-1 (GLP-1) is a potent glucoincretin hormone and an important agent for the treatment of type 2 diabetes. Here we demonstrate that B-cell translocation gene 2 (BTG2) is a...
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Effects of BCG, lymphotoxin and bee venom on insulitis and development of IDDM in non-obese diabetic mice

Kim JY, Cho SH, Kim YW, Jang EC, Park SY, Kim EJ, Lee SK

To investigate whether BCG, lymphtoxin (LT) or bee venom (BV) can prevent insulitis and development of diabetes in non-obese diabetic (NOD) mice, we measured the degree of insulitis and incidence...
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