- Morphine Attenuates Endothelial Cell Adhesion Molecules Induced by the Supernatant of LPS-Stimulated Colon Cancer Cells
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Min TJ, Park SH, Ji YH, Lee YS, Kim TW, Kim JH, Kim WY, Park YC
- KMID: 1785959
- J Korean Med Sci.
- 2011 Jun;26(6):747-752.
- doi: 10.3346/jkms.2011.26.6.747
A large reservoir of bacterial lipopolysaccharide (LPS) is available in the colon and this could promote colon cancer metastasis by enhancing tumor cell adhesion, intravasation, and extravasation. Furthermore, adhesion molecules... -
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- Angiopoietin-1 variant, COMP-Ang1 attenuates hydrogen peroxide-induced acute lung injury
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Kim SR, Lee KS, Park SJ, Min KH, Lee KY, Choe YH, Hong SH, Koh GY, Lee YC
- KMID: 756334
- Exp Mol Med.
- 2008 Jun;40(3):320-331.
- doi: 10.3858/emm.2008.40.3.320
Reactive oxygen species (ROS) play a crucial role in acute lung injury. Tissue inflammation, the increased vascular permeability, and plasma exudation are cardinal features of acute lung injury. Angiopoietin-1 (Ang1)... -
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- Oxidative stress is associated with the number of components of metabolic syndrome: LIPGENE study
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Yubero-Serrano EM, Delgado-Lista J, Pena-Orihuela P, Perez-Martinez P, Fuentes F, Marin C, Tunez I, Jose Tinahones F, Perez-Jimenez F, Roche HM, Lopez-Miranda J
- KMID: 2154247
- Exp Mol Med.
- 2013 Jun;45(6):e28.
Previous evidence supports the important role that oxidative stress (OxS) plays in metabolic syndrome (MetS)-related manifestations. We determined the relationship between the number of MetS components and the degree of... -
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- KR-31543 reduces the production of proinflammatory molecules in human endothelial cells and monocytes and attenuates atherosclerosis in mouse model
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Choi JH, Yoo JY, Kim SO, Yoo SE, Oh GT
- KMID: 1402317
- Exp Mol Med.
- 2012 Dec;44(12):733-739.
KR-31543, (2S, 3R, 4S)-6-amino-4-[N-(4-chlorophenyl)-N-(2-methyl-2H-tetrazol-5-ylmethyl) amino]-3,4-dihydro-2-dimethyoxymethyl-3-hydroxy-2-methyl-2H-1-benz opyran is a new neuroprotective agent for ischemia-reperfusion damage. It has also been reported that KR-31543 has protective effects on lipid peroxidation and H2O2-induced reactive... -
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