- Variation of nuclear and mitochondrial DNAs in Korean and Chinese isolates of Clonorchis sinensis
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Lee SU, Huh S
- KMID: 662786
- Korean J Parasitol.
- 2004 Sep;42(3):145-148.
- doi: 10.3347/kjp.2004.42.3.145
We compared the DNA sequence difference of isolates of Clonorchis sinensis from one Korean (Kimhae) and two Chinese areas (Guangxi and Shenyang). The sequences of nuclear rDNA (18S, internal transcribed... -
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- Genetic variation of the Apo Al-CIII-AIV gene cluster in hypertriglyceridemic patients with chronic renal failure undergoing hemodialysis
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Choi GR, Suh SP, Song JW, Kee SJ, Shin JH, Ryang DW
- KMID: 1128626
- J Korean Med Sci.
- 2000 Jun;15(3):289-294.
- doi: 10.3346/jkms.2000.15.3.289
Many patients with chronic renal failure (CRF) requiring hemodialysis present with hypertriglyceridemia (HTG). But the exact cause of HTG in CRF is still unknown. Genetic variation of the apo AI-CIII-AIV... -
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- Influence of the sequence variations of the HLA-DR promoters derived from human melanoma cell lines on nuclear protein binding and promoter activity
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Lee TJ, Kim SJ, Park JH
- KMID: 1062238
- Yonsei Med J.
- 2000 Oct;41(5):593-599.
- doi: 10.3349/ymj.2000.41.5.593
In previous studies we reported that the expression of HLA-DR on melanoma cell lines was differentially modulated by IFN- gamma and that the transcription rate was responsible for this differential... -
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- Analysis of the variations in IL-28RA gene and their association with allergic rhinitis
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Chae SC, Park YR, Li CS, Lee JH, Yang YS, Zhang Q, Kim KS, Chung HT
- KMID: 1094156
- Exp Mol Med.
- 2006 Jun;38(3):302-309.
IL-28RA is one of the important candidate genes for complex trait of genetic diseases, but there is no published information of the genetic variation in this gene. We scanned the... -
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- Homozygous VN (677C to T) and d/D (2756G to A) variants in the methylenetetrahydrofolate and methionine synthase genes in a case of hyperhomocysteinemia with stroke at young age
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Song KS, Song JW, Choi JR, Kim HK, Shin JS, Kim JH
- KMID: 1085748
- Exp Mol Med.
- 2001 Jun;33(2):106-109.
Hyperhomocysteinemia is known to be associated with an increased risk of myocardial infarction, stroke, peripheral arterial disease, and venous thrombosis. Gene polymorphisms in methylenetetrahydrofolate reductase (MTHFR) and methionine synthase (MS)... -
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- The Haplotype Analyses Using Multiple Markers of the Apolipoprotein B Gene in Patients with Coronary Artery Disease
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Hong SH, Song J, Kim JQ
- KMID: 648351
- J Korean Med Sci.
- 2001 Dec;16(6):719-724.
- doi: 10.3346/jkms.2001.16.6.719
The high level of low density lipoprotein (LDL) is a risk factor for cardiovascular disease. Apolipoprotein (apo) B is a major protein component of LDL and plays an important role... -
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- The Genetic Studies of Obsessive-Compulsive Disorder and Its Future Directions
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Kim SJ, Kim CH
- KMID: 1779492
- Yonsei Med J.
- 2006 Aug;47(4):443-454.
- doi: 10.3349/ymj.2006.47.4.443
Obsessive-compulsive disorder (OCD) is characterized by recurrent and persistent thoughts (obsessions), and repetitive behaviors or mental acts (compulsions). In Korea, an epidemiological study reported that the lifetime prevalence of OCD... -
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- Genetic comparison between Spirometra erinacei and S. mansonoides using PCR-RFLP analysis
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Lee SU, Huh S, Phares CK
- KMID: 1715315
- Korean J Parasitol.
- 1997 Dec;35(4):277-282.
- doi: 10.3347/kjp.1997.35.4.277
The only observed morphological difference between Spirometra erinacei and S. mansonoides is the uterine shape of the mature proglottid. Two species of worms are thought to be evolutionarily closely... -
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- Molecular biological characterization of enterovirus variant isolated from patients with aseptic meningitis
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Jung YT, Kim GR, Paik SY
- KMID: 754995
- Exp Mol Med.
- 1998 Jun;30(2):101-107.
In Korea, there was a big outbreak of aseptic meningitis in 1993. Six clinical isolates of enterovirus were obtained from patients with aseptic meningitis and were identified as echovirus type 9 by... -
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- PCR-RFLP pattern of three kinds of Metagonimus in Korea
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Yu JR, Chung JS, Huh S, Lee SH, Chai JY
- KMID: 1715314
- Korean J Parasitol.
- 1997 Dec;35(4):271-276.
- doi: 10.3347/kjp.1997.35.4.271
We tried to compare the three kinds of Metagonimus species, M. yokogawai, Metagonimus Miyata type, and M. takahashii, which were known to be distributed in Korea with polymerase chain... -
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- Genetic Diversity and Exotoxin A Production of Group A Streptococci Causing Sepsis
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Koh EH, Lee NY, Kim EC, Kim S
- KMID: 1781821
- J Korean Med Sci.
- 2006 Apr;21(2):193-198.
- doi: 10.3346/jkms.2006.21.2.193
The M protein and streptococcus pyrogenic exotoxin (SPE A) are important virulence factors in group A streptococci (GAS) infections. The emm types of GAS strains isolated from patients with sepsis... -
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- Genotype-Phenotype correlation of SMN locus genes in spinal muscular atrophy patients from India
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Kesari A, Idris MM, Chandak GR, Mittal B
- KMID: 1056225
- Exp Mol Med.
- 2005 Jun;37(3):147-154.
Spinal muscular atrophy has been classified into four groups based on the age of onset and clinical severity of the disease. Homozygous deletion in SMN1 gene causes the disease but... -
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- Genetic diversity of Acanthamoeba isolated from ocean sediments
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Liu H, Ha YR, Lee ST, Hong YC, Kong HH, Chung DI
- KMID: 1720506
- Korean J Parasitol.
- 2006 Jun;44(2):117-125.
- doi: 10.3347/kjp.2006.44.2.117
Genetic diversity of 18 Acanthamoeba isolates from ocean sediments was evaluated by comparing mitochondrial (mt) DNA RFLP, 18S rDNA sequences and by examining their cytopathic effects on human corneal epithelial... -
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- Association between interleukin 6 promoter variants and chronic hepatitis B progression
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Park BL, Lee HS, Kim YJ, Kim JY, Jung JH, Kim LH, Shin HD
- KMID: 1097254
- Exp Mol Med.
- 2003 Apr;35(2):76-82.
Interleukin 6 (IL6) plays an essential role in the regulation of immune response to chronic disease. In this study, the three known single nucleotide polymorphisms (SNPs) in the IL6 promoter... -
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- Molecular genetic characterization of alternatively spliced CD44 transcripts in human stomach carcinoma
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Kim YS, Chi SG, Kim YW, Park YK, Yoon C
- KMID: 645110
- J Korean Med Sci.
- 1997 Dec;12(6):505-513.
- doi: 10.3346/jkms.1997.12.6.505
CD44 is a member of cell surface glycoproteins which are involved in cell-matrix adhesion and tumor metastasis. Certain types of tumors express complex CD44 isoforms generated by alternative splicing... -
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- Random amplified polymorphic DNA (RAPD) analysis of Mycobacterium tuberculosis strains in India
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Singh JP, Verma R, Chaudhuri
- KMID: 1059206
- J Vet Sci.
- 2006 Jun;7(2):181-187.
- doi: 10.4142/jvs.2006.7.2.181
The usefulness of random amplification of polymorphic DNA (RAPD) analysis for typing Indian strains of M. tuberculosis was investigated. M. tuberculosis H37Rv, M. tuberculosis DT and 42 clinical isolates of M. tuberculosis were subjected... -
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- Restriction endonuclease analysis of mitochondrial DNA of Acanthamoeba sp. YM-4 (Korean isolate)
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Shin HJ, Im K, Jeon KW
- KMID: 1715326
- Korean J Parasitol.
- 1997 Jun;35(2):119-125.
- doi: 10.3347/kjp.1997.35.2.119
Acanthamoeba sp. YM-4 is similar to A. culbertsoni based upon morphological characteristics of trophozoites and cysts. However, based on other characteristics, pathogenicity to mice, in vitro cytotoxicity and isoenzyme patterns.... -
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- Familial Aggregation of Blood Pressure
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Suh I, Kim IS, Chae YM
- KMID: 693086
- Yonsei Med J.
- 1987 Sep;28(3):199-208.
- doi: 10.3349/ymj.1987.28.3.199
To examine the familial aggregation of blood pressure, household interviews and health examination surveys were conducted from July 9 to August 18, 1986 on 469 families with first grade children... -
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- Association of transforming growth factor-b1 gene polymorphisms with a hepatocellular carcinoma risk in patients with chronic hepatitis B virus infection
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Kim YJ, Lee HS, Im JP, Min BH, Kim HD, Jeong JB, Yoon JH, Kim CY, Kim MS, Kim JY, Jung JH, Kim LH, Park BL, Shin HD
- KMID: 1094701
- Exp Mol Med.
- 2003 Jun;35(3):196-202.
Transforming growth factor-b1 (TGF-beta 1) can act as both a tumor suppressor and a stimulator of tumor progression. We have examined the relationship between polymorphisms of the TGF-beta 1 gene... -
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- Genetic variance of Trichomonas vaginalis isolates by Southern hybridization
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Ryu JS, Min DY, Shin MH, Cho YH
- KMID: 662566
- Korean J Parasitol.
- 1998 Sep;36(3):207-211.
- doi: 10.3347/kjp.1998.36.3.207
In the present study, genomic DNAs were purified from Korean isolates (KT8, KT6, KT-Kim and KT-Lee) and foreign strains (CDC85, IR78 and NYH 286) of Trichomonas vaginalis, and hybridized with... -
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