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Amelioration of Cerebral Ischemic Injury by a Synthetic Seco-nucleoside LMT497

Ryu S, Kwon J, Park H, Choi IY, Hwang S, Gajulapati V, Lee JY, Choi Y, Varani K, Borea PA, Ju C, Kim WK

Recently, we reported that the A3 adenosine receptor (A3AR) agonist LJ529 (2-chloro-N6-(3-iodobnzyl)-5'-N-methylcarbamoyl-4'-thioadenosine) reduces cerebral ischemic injury via inhibition of recruitment of peripheral inflammatory cells into ischemic brain lesion. A3AR agonists,...
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